Academic Pediatric Infectious Disease

摘要 我们华盛顿大学(UW)儿科传染病(PID)培训计划的目标 (TP)是培养未来儿童传染病研究的领导者。我们的TP(1)招聘人员经验丰富 和敬业的儿科医生；(2)对他们进行基础和新颖的分子、基因组、蛋白质组、生物信息学、 和流行病学方法，以及(3)指导他们制定和领导独立的研究计划。 我们要求延长T32支持，以便每年培训四名儿科医生进行研究。最初，每个人 在西雅图儿童医院(SCH)的支持下，参加了为期12个月的临床培训(用于PID认证)。 随后，T32将支持培训学院(TF)进行为期2年的指导性研究，他们是 他们的研究领域和卓越的指导能力。鼓励受训人员和特别工作组处理将 为理解和治疗儿科传染病贡献新的批判性见解，并产生 K、R或其他奖项的初步数据。此外，研究人员还接受教育和实践教育。 管理人类和/或动物研究、赠款和手稿准备的联邦法规，以及 在学术界取得成功的战略。我们的课程包括过渡到K系列NIH的有组织的时间表 奖励，如果需要，我们的部门提供支持，以帮助学员在这一过渡。 我们的NIH T32支持的UW-PID-FP自1981年以来已经培训了94名研究员，并保持着一致的开发记录 母婴健康领域的研究领导者(图1)。在过去的15年里，34名研究员成功地 完成了我们的TP，1个转到了不同的TP，9个是现在的研究员。截至2017年5月，34个TP中 过去15年的毕业生中，有18人(53%)获得了K级证书。在完成TP的毕业生中， 超过5年前(因此在此阶段将发展到NIH R级资助)，11/26(42%) 接收到的R。生物医学研究仍然是最近15届毕业生中26/34(76%)的主要重点 年：17个领导学术实验室(R、K或基金资助的个人资料)，2个学术研究科学家，4个领导 政府机构内有内部资金的研究人员，1人是行业研究人员，2人是 大学生物学教授教授本科生并进行研究。其余8/34(24%) 包括：在学术医院参加研究的2名临床医生教育人员，以及6名临床医生 传染病专家。我们有9名现有研究员和1名新研究员将于2017年7月加入；其中8名 已提交≥1个人K和/或基金会拨款申请；4人获得奖励，6人获得 待处理的申请。在我们现有的研究员和过去15年的应届毕业生(N=43)中，6人(14%) 在卫生科学中代表不足的少数群体(URM)。2017年，两名研究员将完成他们的第三年 奖学金和两人将继续作为四年级高级研究员/讲师，由我系或其 等待K和/或其他赠款申请；另外2人将完成他们的第4年奖学金，其中1人加入 乔治城大学是一名助理教授，另一名目前正在3所大学之间做出选择。

ABSTRACT The objective of our University of Washington’s (UW) Pediatric Infectious Diseases (PID) Training Program (TP) is to train future leaders in research on infectious diseases of children. Our TP (1) recruits experienced and committed pediatricians; (2) trains them in basic and novel molecular, genomic, proteomic, bioinformatic, and epidemiologic methods, and (3) mentors them to develop and lead an independent research program. We request the renewal of T32 support to train four pediatricians in research annually. Initially, each fellow engages in 12 months of clinical training (for PID certification), supported by Seattle Children's Hospital (SCH). Subsequently, the T32 will support 2 years of mentored research by Training Faculty (TF) who are leaders in their areas of research and excel at mentorship. Trainees and TF are encouraged to tackle projects that will contribute novel and critical insights into understanding and treating pediatric infectious diseases and generate preliminary data for a K, R, or other award. In addition, fellows receive didactic and hands-on education in the federal regulations governing research with humans and/or animals, grant and manuscript preparation, and strategies to succeed in academia. Our curriculum includes a structured timeline to transition to “K”-series NIH awards, and if needed, our department extends support to assist trainees in this transition. Our NIH T32-supported UW-PID-FP has trained 94 fellows since 1981, with a consistent record of developing research leaders in Maternal-Child Health (Figure 1). During the past 15 years, 34 fellows have successfully completed our TP, 1 transferred to a different TP, and 9 are current fellows. As of May 2017, of the 34 TP graduates from the past 15 years, 18 (53%) have been awarded Ks. Of the graduates completing our TP more than 5 years ago (and therefore at the stage one would progress to NIH R-level funding), 11/26 (42%) have received Rs. Biomedical research continues to be a primary focus of 26/34 (76%) graduates from the last 15 years: 17 lead academic labs (PIs of R, K or foundation grants), 2 are academic research scientists, 4 are lead researchers within government institutions with intramural funds, 1 is an industry researcher, and 2 are university biology professors teaching undergraduates and performing research. The remaining 8/34 (24%) include: 2 clinician educators at academic hospitals where they participate in research, and 6 clinical specialists in infectious diseases. We have 9 current fellows and 1 new fellow entering in July 2017; 8 of these have submitted ≥1 individual applications for K and/or foundation grants; 4 received awards, and 6 have pending applications. Among our current fellows and recent graduates (N=43) from the past 15 years, 6 (14%) are under-represented-minorities (URM) in health sciences. In 2017, two fellows will complete their 3rd year of fellowship and both will continue as 4th-year Senior Fellows/Instructors with funding by our department or their pending K and/or other grant applications; 2 others will complete their 4th-year of fellowship, one joining Georgetown University as an Assistant Professor and the other currently deciding between 3 university offers.