Stanford Molecular Imaging Scholars (SMIS) Program

项目总结/摘要 该斯坦福大学分子成像学者（SMIS）计划是一个综合的，3年的跨学科 斯坦福大学的博士后培训项目，汇集了来自13个国家的30名教师导师 医学院、工程学院、人文科学学院的各个系。分子成像（MI）， 一种非侵入性技术，用于可视化和量化生物体内特定的分子和生化过程， 生物体，彻底改变了医学和生物医学研究，并继续扩大其应用， 癌症的检测、治疗和管理。持续发展和增长的关键 一个重要的领域是对下一代癌症MI科学家的深入培训。我们建议培训7名 博士后研究生（包括第一、第二和第三年研究员）。SMIS教师导师，以及广泛的 资源，提供丰富多样的培训环境，涵盖生物，物理， 数学、生物计算/生物医学信息学、工程学、化学、生物化学、癌症生物学， 免疫学和医学。SMIS计划的核心是为学员提供机会（ 博士，医学博士或医学博士/博士学位）进行创新的MI研究，由教师共同指导， 互补的研究和临床学科。SMIS学员还参加专门课程， 研讨会、国家会议、临床查房，包括负责任地开展研究的伦理培训， 提高研究的可重复性。3年计划的高潮与准备和 提交NIH赠款提案，以支持受训者过渡到癌症MI的独立职业生涯。 在前三个奖励周期中，39名受训人员参加了SMIS计划;目前有5人在注册 截至本文撰写时，已有34人完成了该计划。那些已经离开的人要么是在教员或其他 学术职位，或在生物技术领域工作。对SMIS培训的需求很高;我们现在 平均每年收到10份或更多合格候选人的申请， 年对于即将到来的周期，我们建议在以下方面加强SMIS计划： 明确包括体内细胞跟踪、免疫治疗和治疗诊断学的程序领域定义，以及 计算;战略性地选择更多不同的导师;改善所有培训和职业生涯 发展组成部分;扩大我们培训委员会的女性领导能力，编写赠款提案 活动，临床接触成分，以及招聘代表性不足的少数民族候选人。的 SMIS计划的持续目标是为有才华的年轻研究人员提供科学和 专业教育/职业发展机会，成为该领域的领导者。

PROJECT SUMMARY/ABSTRACT The Stanford Molecular Imaging Scholars (SMIS) program is an integrated, 3-year cross-disciplinary postdoctoral training program at Stanford University that brings together 30 faculty mentors from 13 departments in the Schools of Medicine, Engineering, and Humanities and Sciences. Molecular imaging (MI), a noninvasive technique to visualize and quantify specific molecular and biochemical processes in living organisms, has revolutionized medicine and biomedical research, and continues to expand its applications in the detection, treatment, and management of cancer. Key to the continued advancement and growth of this important field is the in-depth training of the next generation of cancer MI scientists. We propose to train 7 postdoctoral trainees per year (comprising 1st, 2nd, and 3rd year fellows). SMIS faculty mentors, and extensive resources, provide a rich and diverse training environment spanning fields such as biology, physics, mathematics, biocomputations/biomedical informatics, engineering, chemistry, biochemistry, cancer biology, immunology, and medical sciences. The centerpiece of the SMIS program is the opportunity for trainees (with PhD, MD, or MD/PhD degrees) to conduct innovative MI research that is co-mentored by faculty in complementary research and clinical disciplines. SMIS trainees also engage in specialized coursework, seminars, national conferences, clinical rounds, including ethics training in the responsible conduct of research, and enhancement of research reproducibility. The 3-year program culminates with the preparation and submission of an NIH grant proposal, in support of trainee transition to an independent career in cancer MI. During the previous three award cycles, 39 trainees have entered the SMIS program; 5 are currently enrolled and 34 have completed the program as of this writing. Those who have moved on are either in faculty or other academic positions, or working in the biotechnology field. Demand for the SMIS training is high; we now receive, on average, 10 or more applications per year from qualified candidates for 2-3 new trainee slots per year. For the upcoming cycle, we propose an enriched SMIS program in the following aspects: expansion of MI program area definitions to explicitly include cell tracking in vivo, immunotherapy and theranostics, and computations; strategic selection of additional diverse mentors; improvement in all training and career development components; expansion of female leadership for our training committee, grant writing proposal activity, clinical exposure components, and recruitment of underrepresented minority candidates. The continued goal of the SMIS program is to provide talented young researchers with the scientific and professional educational/career development opportunities to become leaders in the field.