GEROSCIENCE TRAINING PROGRAM IN OKLAHOMA

摘要 人们对衰老和与年龄相关的疾病的病因知之甚少。在过去的30年里，有 在我们对衰老在许多疾病发展中的关键作用的理解方面取得了令人印象深刻的进展 这限制了生活质量。衰老和与年龄相关的疾病显然会导致依赖和严重的 寿命缩短；然而，如果不清楚衰老和疾病之间的相互作用， 无法开发出有效的治疗方法。我们的老年科学培训计划于2017年启动，是一个新的 培训下一代研究人员以解决老龄化及其复杂原因的方法 与年龄相关疾病的相互作用。我们最初请求支持3名博士后和4名博士后 16名教职员工的研究员。在过去的4年里，该计划利用这一支持，总共培训了8名预科医生 博士生和博士后实习生9人。在这一初始资助期内，受训人员总数将 在该计划的-05年继续扩大。特别要注意的是，由于我们的实习生 他们被T32计划录取，经过严格的培训计划，并被要求撰写拨款申请 来支持他们提出的研究。重要的是，由于联邦政府的资助，轮换T32的受训人员 或协会赞助的奖项继续参与并受益于 我们已经确立了。同样，我们的导师每年都会被重新认证，我们还制定了一个培训计划 年轻的导师。博士前学生：在进入我们项目的8名博士前学生中，有7人 已步入正轨或已完成博士学位。75%(75%)的博士前学生(6)拥有 书面拨款申请，在提交申请的申请中，100%已获得资助。重要的是，这些是 主要是F31、R36和AHA赠款。到目前为止，这些受训人员已经出版了4.12份出版物。博士后 研究员：在九(9)名博士后候选人中，到目前为止有七(7)名研究员提交了补助金，其中， 57%的人已经获得了资金。到目前为止，受训人员平均出版了8.91种出版物。我们的绝大多数学生 因其演讲而获得地方和国家奖项。那些已经毕业的人已经找到了工作 在学术和制药环境中。根据我们的成功程度，目前的人口普查和计划 为了继续扩大我们的项目，我们已将我们的指导人员增加到21人，并要求4人 4个研究生和4个博士后实习生职位，继续我们的老年学培训。

ABSTRACT The etiology of aging and age-related disease is poorly understood. Over the past 3 decades, there have been impressive advances in our understanding of the critical role of aging in the development of many diseases that limit quality of life. Aging and diseases associated with age clearly result in dependence and a severe reduction in health-span; however, without a clear understanding of the interactions between aging and disease, effective therapies cannot be developed. Our training program in GeroScience was initiated in 2017 as a new approach to training the next generation of researchers to address the complex causes of aging and their interactions with age-related disease. We originally requested support for 3 pre-doctoral and 4 post-doctoral fellows for 16 faculty. Over the last 4 years, the program has leveraged this support to train a total of 8 pre- doctoral trainees and 9 post-doctoral trainees. The total number of trainees during this initial funding period will continue to expand in the -05 year of the program. It is particularly important to note that as our trainees are accepted to the T32 program, they undergo a rigorous training plan and are required to write grant applications to support their proposed research. Importantly, trainees that rotate off our T32 due to the funding of their Federal or Association sponsored awards continue to participate in, and benefit from, the overall training program that we have established. Similarly, our mentors are recertified each year and we have developed a program to train young mentors. Predoctoral Students: Of the 8 pre-doctoral students that have entered our program, seven (7) are on-track or have completed their PhD. Seventy-five percent (75%) of the pre-doctoral students (6) have written grant applications and, of those submitting applications, 100% have been funded. Importantly, these are primarily F31, R36, and AHA grants. These trainees have produced 4.12 publications to date. Post-Doctoral Fellows: Of the nine (9) post-doctoral candidates, seven (7) fellows have submitted grants thus far and, of these, 57% have received funding. The trainees average 8.91 publications to date. The vast majority of our students have won local and national awards for their presentations. Those that have graduated have found employment in both academic and pharmaceutical environments. Based on our level of success, current census and plans for continued expansion of our program, we have increased our mentoring faculty to 21 and are requesting 4 graduate and 4 post-doctoral trainee positions to continue our training in GeroScience.