CBT by Phone to Promote Use of Alcohol Related Care and Reduce Drinking

新冠肺炎大流行对酒精使用和酒精使用的治疗利用有重大影响 在新冠肺炎的经历中存在明显的种族差异，包括更高的 黑人新冠肺炎感染、住院和死亡情况，成为本新冠肺炎增刊的焦点。 更具体地说，本附录涵盖为期4年的随机对照试验(RCT)的最后2年，以 检查一次电话干预--认知行为疗法寻求治疗的效果 (CBT-TS)，提高AUD治疗利用率，减少饮酒。受试者为患有澳门氏症的成人志愿者 通过社交媒体从纽约罗切斯特地区招募的，以前没有澳大利亚糖尿病治疗史的患者。 在基线评估之后，受试者被随机分为CBT-TS或对照条件(正在阅读 有关AUD治疗的信息手册)，并跟踪6个月。RCT招募一年后， 2020年3月，针对席卷美国的新冠肺炎疫情，全州发布了一项行政命令 纽约市，在全州范围内产生了突然而戏剧性的影响。一个月后，研究小组开始 对新冠肺炎体验进行详细评估，以评估受试者个人对CoVID的暴露- 19、家庭成员暴露、新冠肺炎相关压力、新冠肺炎影响饮酒。穿过 本补编，这些数据在人口一级(由行政命令标明)和个人一级 (通过新冠肺炎评估获得)用于分析与新冠肺炎相关的经验及其 AUD治疗利用、饮酒结果和对该研究的反应与前瞻性关联 干预(具体目标1)，并通过比较黑人和非白人来探索种族差异 拉美裔(特定目标2)。此外，初步研究表明，黑人可能对 CBT-TS干预，强调了进一步研究该人群干预的重要性。至 为了达到这两个研究目标，本补编提供了资源，以增加跟踪调查的时间(从6 月至12个月)，这是建模新冠肺炎体验随时间推移的影响并增加 样本量(从n=450到n=500)，优先考虑增加招募黑人(达到n=100)到 促进与非西班牙裔白人的细分分析和比较。本增刊是为了回应NOT-OD- 20-097，并阐述了国家卫生倡议中的重点，即(新冠肺炎)对下游健康的影响 相关的)社会、行为和经济影响，包括(种族)风险和恢复力的差异。 此外，它还响应了它的呼吁，即“积极资助研究现有的纵向队列，特别是那些 与新冠肺炎事件前后的社会和行为因素相关的大量数据的队列 (新冠肺炎)爆发。按照这些思路，全州范围内的行政命令是在数据的中点发布的 收集，最适合研究接触新冠肺炎前后的队列。

The COVID-19 pandemic has major implications for alcohol use and treatment utilization for alcohol use disorder (AUD), and there are pronounced racial disparities in COVID-19 experiences including higher rates of COVID-19 infections, hospitalizations, and deaths in Blacks, serving as the foci of this COVID-19 supplement. More specifically, this supplement covers the final 2 years of a 4-year randomized controlled trial (RCT) to examine the efficacy of a one-session phone intervention, Cognitive Behavioral Therapy for Treatment Seeking (CBT-TS), to increase AUD treatment utilization and reduce drinking. Subjects are adult volunteers with AUD recruited from the Rochester, New York area through social media who have no prior history of AUD treatment. Following a baseline assessment, subjects are randomized to CBT-TS or a control condition (being read an information pamphlet on AUD treatment) and followed for 6 months. One year into recruitment for the RCT, in March 2020, a statewide executive order was issued in response to the COVID-19 pandemic that swept into New York City, with sudden and dramatic effects throughout the state. A month later, the study team began to administer a detailed assessment of COVID-19 experiences to assess subjects' personal exposure to COVID- 19, exposure of family members, stress related to COVID-19, and alcohol use affected by COVID-19. Through this supplement, these data at the population level (marked by the executive order) and at the individual level (obtained through the COVID-19 assessment) are used to analyze COVID-19 related experiences and their prospective associations with AUD treatment utilization, drinking outcomes, and response to the study intervention (Specific Aim 1) and to explore racial disparities through comparisons of Blacks and white non- Hispanics (Specific Aim 2). Moreover, pilot research suggests that Blacks may be especially responsive to the CBT-TS intervention, underscoring the importance of further study of the intervention in this population. To achieve the two study aims, the supplement provides resources to increase the length of follow-up (from 6 months to 12 months) which is needed to model effects of COVID-19 experiences over time, and to increase the sample size (from n=450 to n=500), with a priority on increased recruitment of Blacks (to reach n=100) to facilitate sub-analyses and comparisons with white non-Hispanics. This supplement is in response to NOT-OD- 20-097 and addresses the emphases in the NOSI on “downstream health impacts resulting from (COVID-19 related) social, behavioral, and economic impacts, including (race) differences in risk and resiliency.” Moreover, it is responsive to its call for “active grants studying existing longitudinal cohorts, particularly those cohorts with considerable data relevant to COVID-19 social and behavioral factors prior and subsequent to the (COVID-19) outbreak.” Along these lines, the statewide executive order was issued at the midpoint of data collection, optimal for the examination of the cohort before and after exposure to COVID-19.