Training Program in Chemosensory Science

摘要 这个T32机构国家研究科学奖提案的总体目标是支持博士前 通过化学传感科学培训计划（TPCS）进行化学传感研究培训， 佛罗里达大学。化学感觉（嗅觉、味觉、化学感觉和内部感觉）的研究 化学传感）对人类健康具有广泛的影响，包括：嗅觉或味觉损伤的影响（例如， 嗅觉丧失、幻味等）饮食、营养、安全、人际关系和 抑郁症;参与正常的嗅觉和味觉，以促进健康饮食;的贡献， 对过度消费及其相关疾病的不适应化学感受行为（例如，糖尿病、 高血压等）;以及通过破坏寻找寄主的过程来控制病媒和寄生虫， 生殖不幸的是，具有适当方法学专业知识的化学传感科学家， 这一多学科领域的必要知识仍然短缺。这种需要创造了一个强大的 推动建立一个综合的博士前培训计划在化学传感科学。化学感受 佛罗里达大学的研究社区-研究问题和方法高度多样化，但 组织和通过用友中心的风味和味道集成-是独特的定位，以引领这一点 计划。TPCS有四个具体目标：（1）进行博士前培训的成功计划， 化学感官科学组成的一个教学课程，一系列的化学感官研究为重点 讨论，指导研究经验，在非学术环境中的实习，患者外展 （2）将博士前实习生与强大的研究导师和 由经验丰富的研究人员组成的多学科委员会;（3）从 国家和地方合格候选人库;（4）从教育方面评估该计划 针对博士前课程的目标。该申请寻求为TPCS提供五年的资金， 最终每年支持四名博士前学生（每名学员两年培训支持两名） 目的是培养能够对科学做出重大贡献的独立科学家， 嗅觉、味觉和化学感觉。在支持期结束时，一个多元化的博士前群体 学员将得到指导和传授先进的方法，基本知识， 多学科方法是进一步化学传感研究的必要条件。此外，我们独特的实习 培训的一部分将为我们的学员提供实质性的接触，以替代职业， 化学传感科学总之，该计划提供了化学传感科学的全面培训 这将有效地为我们的学员准备丰富的化学传感科学职业生涯。

ABSTRACT The overall goal of this T32 Institutional National Research Science Award proposal is to support predoctoral training in chemical senses research through the Training Program in Chemosensory Science (TPCS) at the University of Florida. The study of the chemical senses (smell, taste, chemesthesis and internal chemosensing) has broad impacts on human health, including: the effects of smell or taste impairments (e.g., anosmia, phantom tastes, etc.) on eating, nutrition, safety, interpersonal relationships and the incidence of depression; the engagement of normal smell and taste to promote healthy eating; the contribution of maladaptive chemosensory behaviors to overconsumption and its related diseases (e.g., diabetes, hypertension, etc.); and the control of disease vectors and parasites through disruption of host seeking or reproduction. Unfortunately, chemosensory scientists with the appropriate methodological expertise and requisite knowledge in this multidisciplinary field continue to be in short supply. This need creates a strong impetus for building an integrative predoctoral training program in chemosensory science. The chemosensory research community at the University of Florida – highly diverse in research questions and methodologies, but organized and integrated through the UF Center for Smell and Taste – is uniquely positioned to lead this program.The TPCS has four Specific Aims: (1) To conduct a successful program of predoctoral training in chemosensory science composed of a didactic curriculum, a series of chemical senses research-focused discussions, a mentored research experience, internships in non-academic settings, a patient outreach experience, and professional development; (2) To link predoctoral trainees with strong research mentors and a multidisciplinary committee of experienced investigators; (3) To recruit talented and diverse trainees from national and local pools of eligible candidates; and (4) To evaluate the program in terms of educational objectives tailored to the pre-doctoral program. This application seeks five years' funding for the TPCS to eventually support four predoctoral students per year (two in each of two years of training support per trainee) with the aim of producing independent scientists capable of making significant contributions to the science of smell, taste and chemesthesis. At the conclusion of the period of support, a diverse group of predoctoral trainees will have been mentored and taught the advanced methods, fundamental knowledge, and multidisciplinary approaches necessary to further chemosensory research. Additionally, our unique internship component of training will provide our trainees with substantive exposure to alternative careers in chemosensory science. Together, this program provides a comprehensive training in chemosensory science that will effectively prepare our trainees for the wealth of chemosensory science careers available.