Core C

核心C：征聘、留用和队列管理 摘要 招聘、保留和队列管理核心将协调创建和维护的所有方面 一个登记的纵向研究种群，有10,000只狗。在这项复杂的全国性研究中，有效 与业主和兽医的沟通对于促进准确和及时地提交数据至关重要 有很多种形式。为了确保成功，这个核心将由首席兽医官凯特·克里维博士管理， 在德克萨斯A&M兽医和生物医学学院，以及来自普渡大学的奥黛丽·鲁普尔博士 大学兽医学院，丹尼尔·普罗米斯洛博士，U19研究项目的PI和Dr。 来自康奈尔大学兽医学院的玛尔塔·卡斯特尔哈诺。招聘、留用和 Cohort Management Core将通过一套四个具体目标来实现其总体目标。具体目标1将 招募、管理和维护一支有足够权力解决U19核心假设的队列，包括 为研究部分精心制作狗的品种、性别和年龄的平衡，并代表狗的多样性 美国的车主。CORE C将制作并分发招募材料给兽医和狗狗 所有者；将协调登记请求并选择参与者；并将确保获得知情同意 从拥有者那里得到的并存档了。通过这一竞争性修订，特定目标2将创建一个可持续的生物库 这将通过从井中制造生物标本来服务于DAP和该项目之外的研究人员- 随着时间的推移，具有DAP特征的队列可用于新的调查。具体目标3将建立和维持 促进以最小负担有效收集、跟踪和处理生物检疫和数据的议定书 在参与者身上。核心C将监测与学习有关的体检、问卷和 实验室评估和提交这些活动产生的数据。最后，特定的目标4将创建 基础设施需要回应参与的所有者和兽医提出的问题和关注的问题 关于完成与研究有关的任务，并监督与参与者和参与者之间的持续沟通。

CORE C: RECRUITMENT, RETENTION AND COHORT MANAGEMENT ABSTRACT The Recruitment, Retention and Cohort Management Core will coordinate all aspects of creating and maintaining an enrolled Longitudinal Study Population of 10,000 dogs. In this complex nationwide study, effective communication with owners and veterinarians is paramount to facilitate accurate and timely submission of data in many forms. To ensure success, this core will be governed by the Chief Veterinary Officer, Dr. Kate Creevy, at Texas A&M College of Veterinary Medicine & Biomedical Sciences, along with Dr. Audrey Ruple from Purdue University College of Veterinary Medicine, Dr. Daniel Promislow, the PI of the U19 Research Program, and Dr. Marta Castelhano from Cornell University College of Veterinary Medicine. The Recruitment, Retention and Cohort Management Core will achieve its overall goals through a set of four specific aims. Specific Aim 1 will enroll, manage and maintain a cohort with sufficient power to address the central hypotheses of the U19 including crafting a balance of dog breed, sex and age for the study segments, and representing the diversity of dog owners in the United States. Core C will create and distribute recruitment materials to veterinarians and dog owners; will coordinate enrollment requests and select participants; and will ensure Informed Consent is obtained from owners and archived. Through this Competing Revision, Specific Aim 2 will create a sustainable biobank that will serve both the DAP and researchers outside this project by making biospecimens from the well- characterized DAP cohorts available for new investigations over time. Specific Aim 3 will establish and maintain protocols to facilitate efficient collection, tracking and processing of biospecimens and data with minimal burden on participants. Core C will monitor timely completion of study-related physical examinations, questionnaires and laboratory assessments and submission of data generated by these events. Finally, Specific Aim 4 will create the infrastructure needed to respond to questions and concerns from participating owners and veterinarians regarding completion of study-related tasks, and to oversee ongoing communication with and among participants.