Research Education Core

研究教育部分摘要 哥伦比亚跨学科研究中心研究教育部分(REC)的目标 关于阿尔茨海默病差异(CIRAD)的目的是为指导和职业发展提供机会， 试点研究，以及与来自代表性不足背景的早期调查人员的跨学科合作 对CIRAD主题重点的研究生涯感兴趣，研究阿尔茨海默病的差异 城市西班牙裔和非西班牙裔黑人中的痴呆和相关痴呆(ADRD)，包括生物学、 行为、社会文化和环境风险和弹性因素、生物标记物和照顾。区域经济共同体 将支持：(A)试点研究方案；(B)ADRD研究指导方案；以及(C)指导方案 在健康差距和少数族裔老龄化研究方面。发展一支技术熟练的劳动力队伍有着广泛的需求 用于研究ADRD中的差异。由于美国人口老龄化，患有ADRD的人数 都在增加。在少数民族中，ADRD患者数量的指数增长更大， 尤其是西班牙裔和非西班牙裔黑人，与非西班牙裔白人相比。关于健康的研究 与ADRD相关的差异需要跨学科的方法，其中包括对社会决定因素的研究 健康(SDOH)，行为科学，精神健康，流行病学，ADRD生物标记物，神经心理学， 测量、生物统计学、生物信息学、临床试验和护理。为此，区域经济共同体将利用 CIRAD教职员工的专业知识、阿尔茨海默病研究中心(ADRC)的专业知识和资源 哥伦比亚大学医学中心(CUMC)和纽约市地区的其他知名合作者。这个 REC将由CIRAD首席调查员(PI)卢辛格和曼利领导，他们在 指导ADRD和健康差距方面的早期调查人员。区域经济共同体将通过以下方式实现其目标 具体目标：具体目标1：支持将在早期阶段征集申请的试点项目方案 调查人员来自CUMC和纽约市大都会地区代表性不足的背景 中心的主题重点，每年至少资助3个项目，每个项目至少获得35,000美元的奖励，其中12- 为期数月；具体目标2.为支持试点项目资助的调查员的职业发展， 谁将被命名为RCMAR科学家，通过一个持续的指导计划；具体目标3.支持 指导RCMAR科学家在ADRD的健康差距和少数族裔老龄化研究方面，遵循国家 老龄问题研究所(NIA)差距研究框架；具体目标4.衡量目标1至 3通过与行政核心协调的总结性和形成性进程。

RESEARCH EDUCATION COMPONENT SUMMARY The goal of the Research Education Component (REC) of the Columbia Center for Interdisciplinary Research on Alzheimer’s Disease Disparities (CIRAD) is to provide opportunities for mentoring and career development, pilot studies, and interdisciplinary collaboration to early investigators from under-represented backgrounds interested in a research career in the thematic focus of the CIRAD, research in disparities in Alzheimer’s disease and related dementias (ADRD) among Urban Hispanic and Non-Hispanic Blacks, including biological, behavioral, sociocultural, and environmental risk and resilience factors, biomarkers, and caregiving. The REC will support: (a) a pilot studies program; (b) a mentoring program in ADRD research; and (c) a mentoring program in health disparities and minority aging research. There is extensive need for development of a skilled workforce for the study of disparities in ADRD. Due to the aging of the US population, the numbers of persons with ADRD are increasing. The exponential rise of numbers of people with ADRD is greater among ethnic minorities, particularly Hispanics and non-Hispanic Blacks, compared with Non-Hispanic Whites. The study of health disparities related to ADRD requires a transdisciplinary approach that includes research in social determinants of health (SDOH), behavioral science, mental health, epidemiology, ADRD biomarkers, neuropsychology, measurement, biostatistics, bioinformatics, clinical trials, and caregiving. To this end, the REC will leverage the expertise of CIRAD faculty, the expertise and resources of the Alzheimer’s Disease Research Center (ADRC) at Columbia University Medical Center (CUMC), and other prominent collaborators in the New York City area. The REC will be led by CIRAD principal investigators (PI) Luchsinger and Manly, who have a strong track record of mentoring early investigators in ADRD and health disparities. The REC will achieve its goals through the following specific aims: Specific aim 1: To support a pilot project program that will solicit applications from early stage investigators from under-represented backgrounds at CUMC and the New York City metropolitan area in the thematic focus of the center, and to fund at least 3 projects annually with awards of at least $35,000 each, of 12- months duration; Specific aim 2. To support the career development of investigators funded for pilot projects, who will be named RCMAR Scientists, through a continuing mentoring program; Specific aim 3. To support mentoring of RCMAR Scientists in health disparities and minority aging research in ADRD, following the National Institute on Aging (NIA) disparities research framework; Specific aim 4. To measure success in aims 1 through 3 through summative and formative processes in coordination with the administrative core.