Multidisciplinary Training in Digestive Diseases

项目摘要/摘要 在这次续订申请中，一项成熟的(42年)、成功的多学科培训计划 对于消化系统疾病，我们将继续培养合格的博士后(医学博士和/或博士)。对于学术研究 从事消化系统疾病的职业。我们由36名科学家组成的跨学科全职教职员工支持以下两个方向 潜在的学员：i)以基础/疾病为导向的研究；以及ii)以患者为导向的研究。基础/疾病 定向跟踪仍然是长期的优秀之一，有机会在粘膜免疫学，细胞 围绕再生组织的生物学、肠道神经科学、肝脏病理生物学和新机会 医学/干细胞和转录/表观遗传学。通过以下途径大力支持该路径的培训 与国立卫生研究院资助的梅奥综合癌症中心、梅奥基础科学部的互动 诊所，以及NIH P30消化疾病中心拨款。以病人为中心的赛道，这是教育性的 通过梅奥翻译科学活动中心(CTSA)提供支持，保持培训机会 人类遗传学/流行病学、肥胖症/营养学、人类成像/生理学和医疗保健科学 交付/相对效力，后者是机构重点的新领域。我们继续要求 支持通过目标和共识驱动机制选拔的5名博士后实习生/年 从每年大约100名医学博士、博士或医学博士/博士候选人中脱颖而出，这些候选人来自不同的 临床学科和基础学科。该计划的总体成功继续突出，85%的 来自最近完成10年队列的受训人员(n=24)进入学术医学工作人员 任命和该队列的资金组合，其中包括13个新的联邦拨款(4个K系列，5个R系列， 4名P30飞行员)。了解多样性对培训环境和结果的积极影响，我们正在 目前正经历着我们历史上最多样化的篇章。在本报告所述期间，50%的 实习生是女性，32%的职位都是来自不同背景的申请者。体制性 支持力度也继续很大，而且得到了充分的证明。因此，这一高度确立的培训计划 保持创造性、创新性和活力，从而继续非常成功地实现其 培训个人从事胃肠病学和肝病学的学术工作。

PROJECT SUMMARY/ABSTRACT In this renewal application of an established (42 years), successful multidisciplinary training program in Digestive Diseases, we will continue to train qualified postdoctoral individuals (M.D., and/or Ph.D.) for academic careers in digestive diseases. Our interdisciplinary, full time faculty of 36 scientists supports two tracks for potential trainees: i) basic/disease oriented research; and ii) patient-oriented research. The basic/disease oriented track remains one of long-standing excellence with training opportunities in mucosal immunology, cell biology, enteric neurosciences, liver pathobiology, and new opportunities organized around regenerative medicine/stem cells and transcription/epigenetics. Training in this track is strongly supported through interactions with the NIH funded Mayo Comprehensive Cancer Center, Basic Science Departments at Mayo Clinic, and the NIH P30 Digestive Disease Center grant. The patient-oriented track, which is educationally buttressed through the Mayo Center for Translational Science Activities (CTSA), maintains training opportunities in human genetics/epidemiology, obesity/nutrition, human imaging/physiology, and the science of healthcare delivery/comparative effectiveness, the latter being a new area of institutional focus. We continue to request support for 5 postdoctoral trainees/year that are selected through objective and consensus-driven mechanisms from a talented annual pool of approximately 100 M.D., PhD, or M.D./PhD candidates derived from a variety of clinical and basic disciplines. The overall success of the program continues to be outstanding with 85% of trainees from the most recently completed 10-year cohort (n=24) entering into an academic medicine staff appointment and a funding portfolio from this cohort that includes 13 new federal grants (4 K series, 5 R series, 4 P30 pilots). Understanding the positive impact of diversity on the training environment and outcomes, we are currently experiencing our most diverse chapter in our history. Over the current reporting period 50% of the trainees are women and 32% of appointments were filled with applicants of Diverse Backgrounds. Institutional support also continues to be strong and well documented. Thus, this highly established training program remains creative, innovative, and dynamic, thereby continuing to be highly successful in achieving its goal of training individuals for academic careers in gastroenterology and hepatology.