FUNCTIONAL MRI OF COGNITIVE PROCESSES

本申请中提出的研究的总体目标是 确定皮层功能激活的时空模式， 在执行特定的感知运动认知任务时， 通过高场强（4特斯拉）磁共振成像（4 T- mRI）。 将研究健康人类受试者。 这些任务旨在 测试两大类认知过程的具体假设， 包括心理旋转和记忆扫描，都表现在 个脑袋 这些目标的潜在实现是可以实现的， 4 T-MRI提供的高空间和时间分辨率。 具体目标是：（a）确定心理治疗过程中涉及的领域 旋转和记忆扫描，和（B）测试这些假设， 认知过程涉及（i）特定的顺序激活 皮质区和（ii）某些共同皮质区的激活。 预计这些研究将部分阐明动力学 参与这两种不同认知的神经相关物 流程.

The overall goal of the research proposed in this application is to determine the spatiotemporal patterns of functional activation of cortical areas during performance of specific perceptual-motor cognitive tasks, as revealed by high field strength (4 Tesla) magnetic resonance imaging (4T- mRI). Healthy human subjects will be studied. The tasks are designed to test specific hypotheses of how two major classes of cognitive processes, including mental rotation and memory scanning, are represented in the brain. The potential achievement of these objectives is within reach, due to the high spatial and temporal resolution afforded by the 4T-MRI. The specific aims are to (a) identify the areas involved during mental rotation and memory scanning, and (b) test the hypotheses that these cognitive processes involve (i) the sequential activation of specific cortical areas and (ii) the activation of certain common cortical areas. It is expected that these studies will partially elucidate the dynamical neural correlates involved in these two different kinds of cognitive processes.