QUALITY OF WELL BEING (QWB) SCALE REVISION PROJECT

描述：拟议项目的具体目标是：开发和 验证QWB的自我管理形式，称为QWB-SA; 进行偏好测量研究，以获得评分系统 为QWB-SA;并制定一个视觉特定的评分系统， QWB-SA。 目标1：开发和验证QWB-SA。 目标1涉及几个步骤。 第一 调查人员将扩大QWB中现有的症状列表。 一 QWB-SA草案（已经制定）将发送给15名专家， 审查和评论。 接下来，将对HRQL文献进行内容分析， 执行以确定QWB-SA充分捕获的程度 包括在现有措施中的项目。 QWB进一步修订后， 完成后，QWB-SA将在UCSD多功能关节炎中心进行试点测试。 中心，并与患者在家庭医学诊所。 其次，措施 将在UCSD正在进行的研究和临床研究中进行实地测试 中心. 此外，10%（200）的分层随机样本将 被选中进行进一步研究。 这200名患者将完成 访谈者管理QWB和SF-36，并适当 在两个时间点进行平衡和给药， 分居 为评估所开发信息的准确性而进行的定性分析 将对200名患者的数据进行调查，使用 内部一致性分析方法。 对全文的补充分析 2，000和200的子集，将包括：项目分析，以评估缺失 所有项目的数据率和频率分布;平均值比较 QWB和QWB-SA评分; QWB所有组分的相关性分析， QWB-SA和SF-36，以确定哪一个QWB与 SF-36;以及按人口统计学变量进行的QWB-SA亚组分析，包括 年龄、性别和教育。 将进行QWB的轮廓评分 使用因子分析，预期的聚类包括：身体活动， 社会活动，自我照顾，流动性，疼痛，情绪功能，和 感觉功能 因子得分将通过获得以下各项的总和来创建： 项目反应和因子得分系数分别为每个维度。 目标2：偏好测量研究，以获得一个评分系统， QWB-SA。 加州大学圣地亚哥分校的500名初级保健诊所的病人 将被招募到这一阶段的拟议研究。 他们将 按性别平均划分，所有人都将是成年人，大约40%的人将是 非裔美国人或西班牙裔。 所有参与者将评定完整病例 不同健康状态的描述和组成部分，使用1-100分 规模 对偏好数据的分析将包括两个阶段： 区间标度性质的建立和区间标度性质的发展 判断模型;价值权重估计。 目标3：特定疾病与一般措施。 在这个阶段， 在这项研究中，研究人员建议开发一种视觉特异性评分系统， 对于QWB-SA。 250名患者接受了他们的第一只眼睛 白内障摘除术将被招募到研究中。 参加者必须 年龄超过35岁。 排除标准包括：不能说话 英语;严重听力障碍;认知障碍;患者 同时进行青光眼、角膜或玻璃体视网膜手术; 患有外伤性白内障的患者;以及视力受损的患者， 严重的是，他们无法完成自我管理的形式。 除了 QWB-SA数据，将收集视力数据，患者将 完成VF-14，一个功能状态测量，专门为 视觉问题。 此外，白内障症状评分量表和简短的医疗 将对患者进行共病量表评估。 心理测量 方法将用于评估QWB-SA和 与视力相关的视力特异性测量和视力特异性 结果测量。

DESCRIPTION: The specific aims of the proposed project are: to develop and validate a self-administered form of the QWB, referred to as the QWB-SA; to perform preference measurement studies in order to obtain a scoring system for the QWB-SA; and to develop a vision specific scoring system for the QWB-SA. Aim 1: Develop and validate QWB-SA. Aim 1 involves several steps. First the investigators will expand on the current list of symptoms in the QWB. A draft of the QWB-SA (already developed) will be sent to 15 experts for review and comment. Next, a content analysis of the HRQL literature will be performed to determine the degree to which the QWB-SA adequately captures items included in existing measures. After further revisions of the QWB are complete, the QWB-SA will be pilot tested at the UCSD Multipurpose Arthritis Center, and with patients in Family Medicine Clinics. Next, the measure will be field tested in ongoing studies at UCSD and in clinical research centers. In addition, a stratified random sample of 10 percent (200) will be selected for further study. These 200 patients will complete the interviewer administered QWB and the SF-36, with appropriate counterbalancing and administration at two time points with about one-month separation. A qualitative analysis for assessing the accuracy of information developed in the surveys will be performed on the 200 patients' data, using the Internal Consistency Analysis method. Additional analyses of the full 2,000, and the subset of 200, will include: item analysis to assess missing data rates and frequency distributions for all items; comparisons of mean QWB and QWB-SA scores; correlation analyses of all components of the QWB, QWB-SA and SF-36 to determine which of the QWB's is most correlated with the SF-36; and subanalyses of the QWB-SA by demographic variables, including age, gender, and education. Profile scoring of the QWB will be performed using factor analyses, with expected clusters including: physical activity, social activity, self-care, mobility, pain, emotional functioning, and sensory functioning. Factor scores will be created by obtaining the sum of item responses and factor score coefficients separately for each dimension. Aim 2: Preference measurement study to obtain a scoring system for the QWB-SA. Five hundred patients from the primary care clinics at the UCSD will be recruited into this phase of the proposed research. They will be evenly divided by gender, all will be adults, and about 40 percent will be African American or Hispanic. All participants will rate complete case descriptions and components of different health states, using a 1-100 point scale. Analyses of the preference data will involve two phases: establishment of the interval scale property and the development of the model of judgment; and, estimation of value weights. Aim 3: Disease-specific versus general measure. In this phase of the study, the investigators propose to develop a vision specific scoring system for the QWB-SA. Two hundred fifty patients undergoing their first eye cataract extraction will be recruited into the study. Participants must be older than 35 years of age. Exclusion criteria include: inability to speak English; serious hearing impairment; cognitive impairment; patients undergoing simultaneous glaucoma, corneal or vitro-retinal procedures; patients with traumatic cataracts; and patients with visual impairment so severe that they cannot complete a self-administered form. In addition to the QWB-SA data, data will be collected on visual acuity and patients will complete the VF-14, a functional status measure designed specifically for visual problems. Also, a cataract symptom score scale and a brief medical co-morbidity scale will be administered to the patients. Psychometric methods will be used to evaluate items from the QWB-SA and the vision-specific measures in relation to visual acuity and a vision specific outcome measure.