THERAPY FOR DRUG ABUSERS WITH PSYCHIATRIC COMORBIDITY

可卡因滥用在精神分裂症患者中很常见 治疗环境和结果导致较差的临床结果，包括 更多的住院，自杀未遂，急诊室就诊， 无家可归的时期，以及暴力行为的插曲。个人 这种共病对传统药物滥用的反应很差， 精神治疗。存在着巨大的临床和研究需求 为此开发创新和定义明确的行为疗法 同时解决精神疾病和药物滥用问题的人口 有问题。 这项重新拨款申请建议开发和试行我们的DUAL 诊断复发预防(DDRP)的心理治疗方法 精神分裂症可卡因滥用者的治疗。这已经很有希望了 认知-行为方法整合和修改了传统的 药物滥用复发预防和精神科社交技能培训 (包括精神症状和用药管理)。 这项拨款建议的具体目的是： 1.编写《DDRP治疗师培训手册》和《患者手册》； 2.编制胜任力和遵从性评定量表； 3.制定和实施教学培训计划；以及 4.对DDRP治疗、培训和评级进行试点研究 比例。 在这项为期三年的第一阶段行为心理治疗研究结束时， 我们期望有方法和试点数据来支持第二阶段 疗效试验。

Cocaine abuse is common among schizophrenic patients in mental health treatment settings and results in poor clinical outcomes including increased hospitalizations, suicide attempts, emergency room visits, periods of homelessness, and episodes of violent behavior. Individuals with this comorbidity respond poorly to traditional drug abuse and psychiatric treatments. There exists a great clinical and research need to develop innovative and well defined behavioral therapies for this population which address both the psychiatric and substance abuse problems. This grant re-application proposes to develop and pilot test our Dual Diagnosis Relapse Prevention (DDRP) psychotherapy approach in the treatment of schizophrenic cocaine abusers. This already promising cognitive-behavioral approach integrates and modifies traditional substance abuse relapse prevention and psychiatric social skills training (including psychiatric symptom and medication management). The specific aims of this grant proposal are to: 1. Develop a DDRP Therapist Training Manual & Patient Workbook; 2. Develop Competence & Adherence Rating scales; 3. Develop and conduct a Didactic Training Program; and 4. Perform a Pilot Study of the DDRP Treatment, Training, and Rating Scales. At the end of this three year Stage One behavioral psychotherapy study, we anticipate to have the methods and pilot data to support a Stage Two efficacy trial.