1998 FASEB CONFERENCE ON PROTEIN PHOSPHATASES

描述(申请者的描述)美国协会联合会 关于蛋白质磷酸酶的实验生物学(FASE B)会议将是 于1998年6月28日至7月3日在科罗拉多州铜山举行。这将是 第五届这样的会议，它已经得到了FASEB的授权，因为 1990年、92年、94年和96年会议的成功。此应用程序 寻求对这次会议运作的部分支持。 蛋白质磷酸酶的研究进展迅速，揭示了 这些酶的基本重要性和意想不到的复杂性 信号转导通路，控制细胞和 生理学。在过去的两年里，数十种新的磷酸酶和 磷酸酶调节亚基已被确定。的主要关注点 目前的研究是为了了解这种不同的阵列的功能 磷酸酶及其参与信号传递的多种方式。 蛋白磷酸酶为开发新的 和特定的医药制剂。磷酸酶已经被 被确认为免疫抑制药物、肿瘤促进剂、DNA的目标 肿瘤病毒和各种天然产品毒素。该委员会的成员 双特异性磷酸酶家族最近被鉴定为 肿瘤抑制基因的产物。这次会议将作为一个论坛。 用于传播关于结构、功能的最新信息 以及对这类重要的调控分子的调控。 像其他FASE B夏季会议一样，本次会议将选择大约 150名来自应用程序的参与者，包括来自行业的代表 和学术界。参与者将包括资深科学家、博士后 和研究生。来自中国的新研究人员不断涌入 各学科在这一领域的投入和1998年的会议将是重要的 重点介绍和讨论遗传学、生物化学和 蛋白质磷酸酶的细胞生物学。会议将由八名成员组成。 选定的会议，每个会议有一名讨论领袖和至少六名发言者 来自最近做出重要贡献的调查人员和来自 提交的摘要。这将有助于确保将年轻人包括在内 调查员、妇女和少数民族作为主要参与者。此外, 将组织两次海报会议。在1996年的会议上，60多名 每张海报展示了两天，并提供了另一个重要的 科学交流的格式。

DESCRIPTION (Applicant's Description) The Federation of American Societies for Experimental Biology (FASEB) Conference on Protein Phosphatases will be held from June 28-July 3, 1998, at Copper Mountain, Colorado. This will be the fifth such conference, and it has been authorized by FASEB because of the success of the conferences in 1990, 92, 94 and 96. This application seeks partial support for the operation of this conference. Research on protein phosphatases is proceeding at a rapid pace, revealing the fundamental importance and unexpected complexity of these enzymes in the signal transduction pathways that govern the fundamental aspects of cell and physiology. Within the past two years, dozens of new phosphatases and phosphatase regulatory subunits have been identified. A major focus of current research is to understand the functions of this diverse array of phosphatases and the multiplicity of ways they are involved in signaling. Protein phosphatases offer a significant potential for development of new and specific pharmalogical agents. Phosphatases have already been identified as the targets for immunosuppressant drugs, tumor promoters, DNA tumor viruses and a wide variety of natural product toxins. A member of the family of dual specificity phosphatases has recently been identified as the product of a tumor suppressor gene. This conference will serve as a forum for dissemination of the most recent information on the structure, function and regulation of this important class of regulatory molecules. Like other FASEB Summer conferences, this meeting will select approximately 150 participants from applications, including representatives from industry and academia. Participants will include senior scientists, postdoctorates and graduate students. There is a constant infusion of new researchers from various disciplines into this area and the 1998 conference will be important for a focused presentation and discussion of the genetics, biochemistry and cell biology of protein phosphatases. The Conference will consist of eight sessions, each with a discussion leader and at least six speakers, selected from investigators who have made important recent contributions and from submitted abstracts. This will help to ensure inclusion of young investiga-tors, women and minorities as primary participants. In addition, two poster sessions will be organized. At the 1996 Conference, more than 60 posters were presented for two days each and provided another important format for scientific exchange.