PANEL STUDY OF AGING, BMI AND HEALTH AMONG MEN & WOMEN

描述（改编自研究者摘要）：考虑肥胖 美国最重要的公共卫生问题之一， 将其与过早死亡和某些类型的发病联系起来的证据 包括糖尿病、高血压和心血管疾病。 尽管人们关注肥胖对发病率的影响， 和死亡率，相对较少的研究已经审查了其他方面的 健康相关的生活质量。 拟议的研究旨在 通过应用累积不利条件来解决文献中的这一差距 理论，以更好地了解如何超重可能会影响身体 残疾和自我评估的健康状况。 根据 累积劣势理论，首要的研究问题是： 肥胖对健康的不利影响，通过身体质量指数（BMI）评估， 随着年龄的增长而减少？ 为此，我们提出了两个主要建议。 假设和几个补充假设进行测试： 假设1. BMI对功能障碍的影响随着 年龄 (This一种假说预测，高BMI会产生更多的 生命过程中的异质性和健康不平等）。 假设2. BMI对健康评估的负面影响随着年龄的增长而增加。 （更多） 一般来说，这一假设预期高BMI会降低健康等级 并导致生命过程中健康下降的恶性循环）。 本研究通过两个全国性的代表性小组对这些假设进行了检验 问题研究 （1）全国健康和营养调查一： 流行病学随访研究（NHEFS）是一项为期20年的四波小组研究， 成年美国人（基线时N= 6，931）。 （2）美国人改变生活（ACL） 是一项针对美国成年人的为期3年的两波小组研究（基线时N= 3，617 包括非裔美国人和老年受试者的过量样本）。 两 具体目标是先进的检验假设：（1）检查 男性体重指数与功能残疾之间的关系， 妇女在小组研究期间和（2）模型的关系 体重指数和评估的健康之间的关系 发病率和功能残疾。 统计分析说明， 通过应用选择偏差模型，研究了由于死亡率导致的自然减员。

DESCRIPTION (adapted from investigator's abstract): Obesity is considered one of the nation's most important public health problems because of the evidence linking it with premature mortality and certain types of morbidity including diabetes mellitus, hypertension, and cardiovascular disease. Despite the attention given to studying the effect of obesity on morbidity and mortality, relatively little research has examined other dimensions of health-related quality of life. The proposed research is designed to address this gap in the literature by applying cumulative disadvantage theory to better understand how excess body weight may affect physical disability and self-assessed health across the life course. According to cumulative disadvantage theory, the overarching research question is: Do the health disadvantages of obesity, assessed by body mass index (BMI), increase of decrease with age? Toward this end, we propose two main hypotheses and several supplementary hypotheses to be tested: Hypothesis 1. The effect of BMI on functional disability increases with age. (This hypothesis anticipates that high BMI will produce more heterogeneity and health inequality over the life course). Hypothesis 2. The negative effect of BMI on health assessments increases with age. (More generally, this hypothesis anticipates that a high BMI lowers health ratings and leads to a pernicious cycle of health decline over the life course). The research tests these hypotheses with two nationally representative panel studies. (1)The National Health and Nutrition Examination Survey I: Epidemiologic Follow-up Study (NHEFS) is a four-wave, 20-year panel study of adult Americans (N=6,931 at baseline). (2)Americans' Changing Lives (ACL) is two-wave, 3-year panel study of adult Americans (N=3,617 at baseline including over-samples of African-American and elderly subjects). Two specific aims are advanced to test the hypotheses: (1) examine the relationship between body mass index and functional disability among men and women over the duration of the panel studies and (2) model the relationship between body mass index and assessed health over time controlling for morbidity and functional disability. The statistical analyses account for attrition due to mortality by applying selection bias models.