Enduring Effects of Early Adversity on Adult Health?

早期逆境对成人健康的持久影响？

• 批准号: 7896774
• 负责人: KENNETH F. FERRARO
• 金额: $ 26.28万
• 依托单位: PURDUE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-08-01 至 2012-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7896774
• 关键词: Accounting; Adult; Age; American; Attention; Child Abuse; Childhood; Cicatrix; Clinical; Communities; Cost Control; Data; Data Sources; Development; Disadvantaged; Disease; Elderly; Epidemiology; Evaluation; Event; Force of Gravity; Future Generations; Health; Healthcare; Inequality; Interview; Life; Life Cycle Stages; Link; Mediating; Mediation; Modeling; Modification; Morbidity - disease rate; Outcome; Patient Self-Report; Perception; Persons; Play; Process; Prospective Studies; Psychophysiologic Disorders; Reporting; Research; Resources; Respondent; Role; Shapes; Surveys; Techniques; Testing; United States; deprivation; design; disability; effective intervention; experience; middle age; psychosocial; public health relevance; socioeconomics; theories

DESCRIPTION (provided by applicant): The study of adult health is being transformed by an emerging body of research linking early- life events and experiences with outcomes in adulthood and later life. The overall aim of this research is to build upon epidemiologic models of the life course to explicate the mechanisms by which multiple forms of early adversity compromise health. Previous research has demonstrated the gravity of early adversity on the life course, but relatively little attention has been given to the situational and reflexive aspects of the self that may shape psychosomatic processes. The proposed research draws upon cumulative inequality theory to examine the role that psychosocial and socioeconomic resources play in mediating the relationship between multiple childhood adversities and adult health. Data for this study come from two waves of the National Survey of Midlife Development in the United States (MIDUS). MIDUS surveyed 3,034 adults (ages 25-74) in 1995, and 2,257 respondents were re-interviewed in 2005, providing a decade of observation and the opportunity to observe incident morbidity, change in disability and self-reported health, and the modification of perceived life trajectories. This study has three specific aims: 1. To identify which early adversities are most consequential to adult health and explicate the accumulation processes associated with early adversity. 2. To examine the extent to which resources and perceptions of life trajectories mediate the relationship between childhood adversity and adult health. 3. To consider whether more positive perceptions of life trajectories reduce the rate of health decline between waves and counteract the noxious effects of early disadvantage. The hypotheses, derived from the above aims, will be tested with a variety of multivariate analytic techniques to estimate direct and indirect effects of early adversity on adult health, with formal tests of mediation. PUBLIC HEALTH RELEVANCE: This research attempts to explicate how childhood conditions shape health conditions during adulthood. Clarifying the link between early disadvantage and adult disease will enable development of effective strategies to reduce health problems for future generations. As healthcare policymakers continue to search for affordable cost- containment strategies, it is becoming increasingly important to understand adult health and illness in a life course perspective.

描述(由申请人提供)：成人健康研究正在被一个新兴的研究机构转变，该研究将早期生活事件和经历与成年和晚年生活的结果联系起来。这项研究的总体目标是建立生命过程的流行病学模型，以解释多种形式的早期逆境危害健康的机制。以前的研究已经证明了早期逆境在生活过程中的严重性，但对可能塑造心身过程的自我的情景和反身方面的关注相对较少。这项拟议的研究利用累积不平等理论来考察心理社会和社会经济资源在调节儿童时期的多重逆境和成人健康之间的关系中所起的作用。这项研究的数据来自美国中年发展全国调查(MIDUS)的两次浪潮。1995年，MIDUS调查了3034名成年人(25岁至74岁)，2005年对2257名受访者进行了重新访谈，提供了十年的观察时间，并有机会观察事件发病率、残疾和自我报告健康的变化，以及感知生活轨迹的改变。这项研究有三个具体目的：1.确定哪些早期逆境对成人健康影响最大，并阐明与早期逆境相关的积累过程。2.考察资源和对生活轨迹的感知在多大程度上调节童年逆境和成人健康之间的关系。3.考虑对生活轨迹的更积极的看法是否会减少两波之间健康下降的速度，并抵消早期不利因素的有害影响。根据上述目标得出的假设，将通过各种多变量分析技术进行检验，以评估早期逆境对成人健康的直接和间接影响，并进行正式的中介测试。公共卫生相关性：这项研究试图解释儿童状况如何影响成年后的健康状况。澄清早期劣势和成人疾病之间的联系将有助于制定有效的战略，减少子孙后代的健康问题。随着医疗政策制定者继续寻找负担得起的成本控制策略，从生命过程的角度理解成年人的健康和疾病变得越来越重要。

项目成果

Alternative Measures of Self-Rated Health for Predicting Mortality Among Older People: Is Past or Future Orientation More Important?

• DOI: 10.1093/geront/gnt098
• 发表时间: 2015-10-01
• 期刊: GERONTOLOGIST
• 影响因子: 5.7
• 作者: Ferraro, Kenneth F.;Wilkinson, Lindsay R.
• 通讯作者: Wilkinson, Lindsay R.

Childhood misfortune and adult health: enduring and cascadic effects on somatic and psychological symptoms?

童年不幸和成年健康：对躯体和心理症状的持久和连锁影响？

• DOI: 10.1177/0898264312464884
• 发表时间: 2013
• 期刊: Journal of aging and health
• 影响因子: 2.8
• 作者: Schafer,MarkusH;Ferraro,KennethF
• 通讯作者: Ferraro,KennethF

Age and the tenses of life satisfaction.

年龄和生活满意度的时态。

• DOI: 10.1093/geronb/gbt038
• 发表时间: 2013
• 期刊: The journals of gerontology. Series B, Psychological sciences and social sciences
• 作者: Schafer,MarkusH;Mustillo,SarahA;Ferraro,KennethF
• 通讯作者: Ferraro,KennethF

Does childhood misfortune raise the risk of acute myocardial infarction in adulthood?

• DOI: 10.1016/j.socscimed.2013.11.026
• 发表时间: 2014-03-01
• 期刊: SOCIAL SCIENCE & MEDICINE
• 影响因子: 5.4
• 作者: Morton, Patricia M.;Mustillo, Sarah A.;Ferraro, Kenneth F.
• 通讯作者: Ferraro, Kenneth F.