CONFERENCE ON MOLECULAR ASPECTS OF EXERCISE AND AGING

衰老与骨骼肌质量和功能的显著和实质性丧失、体脂增加以及骨质疏松症、2型糖尿病、高血压和动脉粥样硬化等慢性病的患病率更高相关。此外，肌肉质量和功能的丧失与老年人功能能力的降低和独立性的丧失有关。体力活动和不运动会产生大量的急性和慢性影响。在老年人中，运动已被证明对肌肉代谢和功能、葡萄糖耐量和胰岛素作用、血脂、脂蛋白、心血管功能和有氧能力以及骨密度有许多显著的积极影响。这次会议是第11届运动生物化学国际会议，将通过聚集来自世界各地从事运动和衰老相关领域工作的科学家来致力于运动对老年人的益处这一主题。这次会议的主题是“运动与衰老的分子方面”。这些会议每三年只举行一次，这次会议将是自1982年(波士顿)以来首次在美国举行。这次会议的选定参与者是与年龄相关的分子和细胞对不活动和体力活动的适应领域的杰出领导者。该提案介绍了讨论的主题和拟议的发言者。我们提议召开一次为期四天的会议，全面研究骨骼肌、心血管系统、骨骼和脂肪细胞的细胞和分子机制。此外，衰老和活动对碳水化合物、脂肪、蛋白质和能量代谢的生理和分子影响将是本次会议的关键特点。这次会议面向来自不同领域、积极从事研究的科学家。会议的规模将受到限制，以便为与会者的讨论和互动提供真正的机会。需要资金提供往返会议地点阿肯色州小石城的交通和住宿费用。会议将以关于衰老和体力活动的分子方面的主旨演讲开始。这次会议还将以免费交流和海报会议的形式介绍原始数据。摘要将被出版，会议记录将作为一本书出版，系列的第十一卷，运动的生物化学。这次会议将是一次对运动和衰老的生物化学感兴趣并积极参与的国际学者和科学家的独特会议。

Aging is associated with a significant and substantial loss of skeletal muscle mass and function, increased body fat, and a greater prevalence of chronic diseases such as osteoporosis, type 2 diabetes, hypertension, and atherosclerosis. In addition, losses of muscle mass and function are associated with reduced functional capacity in the elderly and loss of independence. Physical activity and inactivity produce a vast array of acute and chronic effects. In elderly people, exercise has been demonstrated to have a number of remarkably positive effects on muscle metabolism and function, glucose tolerance and insulin action, serum lipids, lipoproteins, cardiovascular function and aerobic power, and bone mineral density. This conference, the 11th International Conference on the Biochemistry of Exercise, will be devoted to the theme of benefits of exercise in elderly people by bringing together scientists from all over the world who are working in areas related to exercise and aging. The theme of the proposed meeting is "Molecular Aspects of Exercise and Aging." These meetings are held only once every three years, and this meeting will be the first to be held in the United States since 1982 (Boston). The selected participants in this conference are prominent leaders in areas related to age associated molecular and cellular adaptations to inactivity and physical activity. This proposal describes the topics for discussion and the proposed speakers. We have proposed a four day conference which will provide a comprehensive examination of cellular and molecular mechanisms in skeletal muscle, the cardiovascular system, bone, and adipocytes. In addition, physiological and molecular effects of aging and activity on carbohydrate, fat, protein, and energy metabolism will be critical features of this conference. This conference is intended for scientists from diverse areas who are actively engaged in research. It will be limited in size to provide a genuine opportunity for discussion and interaction of participants. Funds are requested to provide transportation and lodging costs to and from Little Rock, Arkansas, the site of the meeting. The conference will begin with a Keynote address in molecular aspects of aging and physical activity. This conference will also consist of the presentation of original data in the form of free communications and poster sessions. Abstracts will be published and the proceedings will be published as a book, volume XI of the series, Biochemistry of Exercise. This conference will be a unique meeting of international scholars and scientists interested and actively involved in the area of the biochemistry of exercise and aging.