CESIUM IODIDE CONVERTER FOR RADIATION THERAPY
CESIUM IODIDE CONVERTER FOR RADIATION THERAPY
批准号:
6072457
负责人:
GERALD ENTINE
金额:
$10.0万
依托单位国家:
美国
项目类别:
财政年份:
2000
资助国家:
美国
项目状态:
已结题
起止时间:
2000-01-14 至 2000-12-31
中文摘要
描述:研究人员建议测试开发一种
通过浇铸碘化铯的高能X射线的更有效的区域探测器
转换器插入金属蜂窝结构的孔中,并通过以下方式阅读
非晶硅二极管阵列,如他们的摘要进一步描述的:
“放射治疗中快速射野成像的最有前途的新方法之一
治疗是目前正在开发的大面积数字探测器。这些
系统使用非晶硅(a:Si)二极管的二维阵列,
生成图像,并具有几个理想的方面,包括能够
实时生成图像。当前门户网站的一个基本问题是
成像设备的一个缺点是固有的X射线光子探测灵敏度
小了当使用可接受的患者剂量时,这种低灵敏度导致
由于有限的图像对比度分辨率导致图像质量差。这个可怜的形象
质量限制了病人护理的实用性。
“实现射野成像显著改善的关键是使用
a:采用高效率的硅转换屏。我们建议开发一种改良的
使用非常厚的分段闪烁体的二维成像系统
与a:Si探测器集成以实现这种改进。这具有的
潜在的显着提高所得的图像质量。研究将
以生产大面积、厚分段的X射线成像转换器
具有改进的对高能X射线的阻止能力,
亚毫米空间分辨率该方法包括注射
闪烁体材料到金属准直器基质中。该方法
克服了标准制造工艺的局限性,
制造大面积分段X射线的成本有效的技术
冰箱。
“在第一阶段计划中,我们将集中精力研究生产高质量的
质量,有限的区域转换器。在第二阶段计划中,转换器将
可按比例放大到射野成像尺寸,
功能a:硅成像系统。"
拟议商业应用:不可用
英文摘要
DESCRIPTION: The investigators propose to test the feasibility of developing a
more efficient area detector for high energy x-rays by casting cesium iodide
converter into the holes of a metal honeycomb structure and reading out by
amorphous silicon diode array, as further described by their abstract:
"One of the most promising new approaches for rapid portal imaging in radiation
therapy are the large area digital detectors currently under development. These
systems use a two-dimensional array of amorphous silicon (a:Si) diodes to
generate an image and have several desirable aspects, including the ability to
produce an image in real-time. A fundamental problem with current portal
imaging devices is that the inherent x-ray photon detection sensitivity is
small. When acceptable patient doses are used, this low sensitivity results in
poor image quality due to limited image contrast resolution. This poor image
quality limits the usefulness in patient care.
"A key to achieving significant improvement in portal imaging is the use of
a:Si with a high efficiency converter screen. We propose to develop a modified
two-dimensional imaging system using a very thick segmented scintillator
integrated with the a:Si detector to achieve this improvement. This has the
potential to significantly improve the resulting image quality. Research will
be carried out to produce large-area, thick segmented x-ray imaging converters
with improved stopping power for high energy x-rays while providing a
submillimeter spatial resolution. This method involves injection of the
scintillator material into a metal collimater matrix. The proposed method
overcomes limitations of standard fabrication procedures by producing a
cost-effective technique of fabricating large-area segmented x-ray
scintillators.
"In the Phase I program, we shall concentrate on the research of producing high
quality, limited area converters. In the Phase II program, the converter will
be scaled up to portal imaging dimensions and incorporated into a fully
functional a:Si imaging system."
PROPOSED COMMERCIAL APPLICATION: NOT AVAILABLE
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
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海外基金