G-WAVE EQUIPMENT TO DETECT SPECIFIC LANGUAGE IMPAIRMENT

（摘自申请人摘要）。 特殊语言障碍的特点是在处理快速， 短听觉刺激。这一赤字可能说明了一些国家在这方面的困难。 人们在语言理解和表达方面（即，阅读障碍）。AMS （声学修改的语音）训练，首先减少， 系统地增加刺激呈现率已被证明是一个 有效治疗。然而，没有可用的电诊断方法 来检测和诊断SLI申请人已经确定了一个 短暂的“振荡”诱发反应以前没有记录在人类或 动物这些反应，称为G波，有可能用于检测 在SLI受试者中存在差异，因为G波明显受到 刺激重复率最佳刺激所需的设备，以检测 SLI功能障碍需要确定。本项目设计的设备 当大脑的功能低于 在SLI中最佳，因此与人类健康有关。随着持续的成功， AMS培训可以预测，诊断设备的市场将 开发.第一阶段项目的具体目标是开发 计算机生成所需的复杂音调刺激的技术， 该项目，并测试所产生的诱发反应是否可以区分 SLI受试者和对照。 拟定商业应用： 如果成功，计算机系统将为电诊断提供依据。 医疗条件。

(Adapted from Applicant's Abstract). Specific language impairment is characterized by deficits in processing rapid, short auditory stimuli. This deficit may account for the difficulties that some persons have in language comprehension and expression (i.e., dyslexia). AMS (acoustically modified speech) training which first decreases and the systematically increases stimulus presentation rate has been shown to be an effective treatment. However, there is no electro-diagnostic method available to detect and diagnose the SLI condition. The applicants have identified a transient "oscillatory" evoked response not previously recorded in humans or animals. These responses, called G waves, have potential for the detection of differences in SLI subjects because G-waves are markedly affected by the stimulus repetition rate. The equipment necessary for optimal stimuli to detect SLI dysfunction needs to be determined. The equipment designed on this project will have relevance to the functioning of the brain when it functions less-than optimally in SLI and thus is related to human health. With continued success of AMS training it can be predicted that a market for diagnostic equipment will develop. The specific aims of this Phase I project are to develop the techniques for a computer to generate the complex tone pip stimuli needed for the project and to test whether the resulting evoked responses can distinguish SLI subjects and controls. PROPOSED COMMERCIAL APPLICATION: If successful, the computer system will provide a basis for electro-diagnosis of this medical condition.