Measuring pain in livestock: mechanisms, objective biomarkers and treatments

该项目旨在创建一种客观的血液测试来衡量牲畜的疼痛，并通过靶向大脑和脊髓的免疫学来创建一种治疗持续性疼痛的新药物。该项目希望产生关于神经免疫系统参与产生和维持持续性疼痛的新知识，以及如何通过创新地使用外周血液测试来量化这种疼痛。该项目的预期结果包括能够量化当前疼痛体验程度的血液测试，以及对动物经历过的疼痛的累积生命测量。这将通过改进最佳实践为澳大利亚畜牧业带来显著的好处。

This project aims to create an objective blood test to measure pain in livestock, and to create a new drug treatment for persistent pain by targeting the immunology of the brain and spinal cord. This project expects to generate new knowledge of the involvement of the neuro-immune system in the creation and maintenance of persistent pain and how this can be quantified through the innovative use of peripheral blood tests. Expected outcomes of this project include a blood test capable of quantifying the extent of current pain experience, and a cumulative life measure of pain an animal has experienced. This should provide significant benefits to the Australian livestock industry by improving best practice.