GRADUATE TRAINING IN MOLECULAR BIOLOGY AND BIOPHYSICS

请继续支持俄勒冈大学正在进行的分子生物学和生物物理学研究生研究培训项目。这项培训活动以分子生物学研究所为中心，也涉及其他具有相关科学兴趣的研究小组。该研究所是一个研究和研究指导中心，在生物大分子的特性中可以找到对生物现象的理解。目前的研究包括研究病毒、细菌、酵母和高等生物细胞的遗传机制的分子基础；基因表达的控制，包括DNA复制、转录和翻译中的起始、延伸和终止机制；酶的结构和功能；蛋白质与核酸的相互作用；以及发育生物学和分化的某些方面。在过去的十年里，研究项目得到了扩展，部分原因是马基信托基金的一项重大资助。此外，由于一个主要的建筑项目，可用的研究空间大大增加了。由于精心规划，所有分子生物学空间仍然紧密相连，不同实验室的研究小组和学员之间的互动仍然很强。教师在不同的院系（生物、化学和物理）担任学术职务，但被安置在相邻的实验室，以最大限度地发挥互动和合作。跨学科的灵活性是通过有机会在任何部门的教师指导下进行研究来促进的。要求将目前的受训人员人数从17人增加到19人。

Continued support is requested for an ongoing program of graduate research training in molecular biology and biophysics at the University of Oregon. This training activity is centered in the Institute of Molecular Biology, and also involves additional research groups with related scientific interests. The Institute is a center for research and research instruction in areas where understanding of biological phenomena can be found in the properties of biological macromolecules. Current research includes studies of the molecular bases of genetic mechanisms in viruses, bacteria, yeast, and cells of higher organisms; control of gene expression, including initiation, elongation, and termination mechanisms in DNA replication, transcription, and translation; enzyme structure and function; interactions of proteins and nucleic acids; and certain aspects of developmental biology and differentiation. Over the last decade the research programs have expanded, in part as a consequence of a major grant from the Markey Trust. In addition, available research space has increased substantially as a consequence of a major building program. Due to careful planning, all molecular biology space is still closely contiguous and interactions between research groups and trainees in different laboratories remain strong. Faculty holds academic appointments in different departments (Biology, Chemistry, and Physics), but are housed in adjacent laboratories to maximize interactions and collaboration. Inter-disciplinary flexibility is promoted by the opportunity to do research under faculty members from any department. An increase in the current number of trainees is requested from 17 to 19.