CEREBRAL BLOOD FLOW IN DEPRESSION AND SCHIZOPHRENIA

局部脑血流量(RCBF)将通过133Xenon测量 抑郁症和精神分裂症患者的吸入性研究 与正常对照组相匹配。这项研究的目的是确定 与这些疾病及其亚型相关的rCBF。90名患者 被诊断为抑郁症和他们的对照将在一年多的时间里进行研究 期限为两年。RCBF测量和评级量表量化 将进行精神病理学检查。一小群二十五人 患者将被安排在标准化的治疗时间表上聚集 关于治疗对rCBF影响的先导数据。关于一百二十个 被诊断为精神分裂症的患者和他们的对照组将有 他们的脑血流量测量和评定量表评估 进行了精神病理学检查。这项研究将在一段时间内进行 三年了。就像抑郁症患者的情况一样， 患者将被安排在标准化的治疗时间表上聚集 关于治疗对rCBF影响的试点信息。

Regional cerebral blood flow (rCBF) will be measured via 133Xenon inhalation in groups of patients with depression and schizophrenia and matched normal controls. The study is aimed at identifying patterns of rCBF associated with these illnesses and their sub types. Ninety patients with a diagnosis of depression and their controls will be studied over a period of two years. rCBF measurement and rating scale quantification of psychopathology will be carried out. A small subgroup of twenty-five patients will be placed on a standardized treatment schedule to gather pilot data on the effect of treatment on rCBF. On hundred and twenty patients with a diagnosis of schizophrenia and their controls will have their cerebral blood flow measurement and rating scale assessment of psychopathology carried out. This study will take place over a period of three years. Like in the case of depressed patients, a subgroup of patients will be placed on a standardized treatment schedule to gather pilot information about the effect of treatment on rCBF.