LIPOSOME ENCAPSULATED B-10 FOR NEUTRON CAPTURE THERAPY

中子俘获疗法是一种有吸引力的标准替代疗法 用于癌症治疗的放射技术，如果核如10B， 可以选择性地集中在肿瘤中。 已知小的单层磷脂小泡被吸收。 动物和人类的肿瘤。脂质体制剂将是 测试了它们稳定包裹高浓度的能力 一种含硼化合物。这些含B化合物的生物分布 脂质体将在携带EMT6肿瘤的小鼠身上进行测试，使用 放射性碘标记的Na2B10 H10。

Neutron capture therapy is an attractive alternative to standard radiation techniques for cancer treatment, if nuclei such as 10B, can be selectively concentrated in tumors. Small, unilamellar phospholipids vesicles are known to be taken up by animal and human tumors. Liposome formulations will be tested for their ability to stably encapsulate high concentrations of boron compounds. Biodistribution of these B-containing liposomes will be tested in mice bearing EMT6 tumors using radioiodine-labeled Na2 B10 H10.