Core Equipment to underpin the National Crystallography Service 2020-

响应这一号召的战略是提供一种平衡的方法，以确保具有前瞻性组件的基本更换设备的安全，这是通过将“投资节约”和“支持多用户设备”这两个方面结合起来实现的。再加上支持和支持ECR和博士生的既定途径，国家晶体服务(NCS)能够接触到所有核心设备调用对象。NCS是世界知名的机构，拥有庞大的用户基础，是第一个建立的国家研究机构(1981)。NRF非常适合于最大限度地提高核心设备投资的效益和受益者，是一种覆盖全国的先进设施，是一种维护和扩大其用户基础的既定、协调的方法。NRF模式提供准入机制、专家支持、监测、治理和可持续运营模式，以确保这项投资将充分发挥其最大潜力。通过参与NCS的正式治理和审查程序，已确定主要设备项目-新测角器。因此，它是一个面临风险的真正关键的设备部件，它的更换将使NCS能够继续保持高水平的性能和吞吐量。NCS核心业务的继续高标准交付将得到引进高性能显微镜的支持，该显微镜将提供新的能力以及更多的冗余和更高的吞吐量。另外两项设备，一个智能测角仪测头和一个低温恒温器，将支持NCS的技术开发方面。前者将提供一种全新的方法来减轻样品的腐烂，并将与仪器制造商共同开发。后者将完成一笔400k GB的设备贷款，以支持基于水晶海绵技术的全新能力。这项工作是与默克公司和Rigaku公司合作的联合开发/影响项目，这将使获得关于纳米升材料或不易结晶的物质的结构数据成为可能。其目的是使其成为NCS服务提供的一个新组成部分，并在已经建立战略伙伴关系的情况下，开发并显著影响学术界和工业界的新的结晶学用户群体。NCS在社区中的独特地位和覆盖范围将使这项设备投资的受益者人数通过其核心业务、先进方法和技术开发工作最大化。庞大的现有用户群覆盖了博士生和ECR--所有这些人都有机会接受这种设备提供的技能培训。总之，在能够继续保持高水平的服务提供的情况下，NCS还可以通过与主要行业和仪器制造商的合作伙伴关系，通过完善的路线和明确确定的影响路径，为这项投资增加显著价值。

The strategy in answering this call is to provide a balanced approach to secure essential replacement equipment with a forward-looking component and this is achieved by bringing together the two strands of 'invest to save' and 'underpinning multi-user equipment'. Coupled with established routes to supporting and enabling ECRs and doctoral students, the National Crystallography Service (NCS) is able to touch on all the Core Equipment call objectives.The NCS is a world-renowned facility with a large user base and was the first National Research Facility to be established (1981). This NRF is ideally suited to maximising the benefits and beneficiaries of a Core Equipment investment, being an advanced facility with a national reach and an established, coordinated approach to maintaining and expanding its user base. The NRF model provides the access mechanisms, expert support, monitoring, governance and sustainable operating model to ensure that this investment will be fully realised to its maximum potential.The main equipment item, a new goniometer, has been identified through involving the formal governance and review procedures of the NCS. It is therefore a truly key equipment component that is at risk and its replacement will enable a continued high level of performance and throughput of the NCS. The continued delivery of NCS core business at a high standard will be supported by the introduction of a high-powered microscope which will provide new capability as well as more redundancy and higher throughput. The other two items of equipment, an Intelligent Goniometer Head and a cryostat, will support the technique development aspect of the NCS. The former will provide an entirely new approach to mitigating against sample decay and would be developed with the instrument manufacturer. The latter will complete a £400k equipment loan to underpin an entirely new capability based around the crystal sponge technique. This endeavour is a joint development/impact project partnering with Merck and Rigaku companies, which would enable acquisition of structural data on nanolitres of material or substances that don't readily crystallise. The aim is for this to become a new component of the NCS service provision and with strategic partnerships already in place, it will develop and significantly impact new crystallography user communities in academia and industry. The unique position and reach of the NCS in the community will enable maximisation of the number of beneficiaries of this equipment investment through its core business, advanced methods and technique development work. The large established user base reaches through to PhD students and ECRs - all of whom would have opportunity for skills training provided with this equipment. In conclusion, with the ability to continue to sustain the high level of service provision, the NCS can also add significant value to this investment through well-established routes and clearly identified pathways to impact via partnerships with key industry and instrument manufacturers.