FREQUENCY OF HEPATITIS C VIRUS RNA AND HEPATITIS C VIRUS SEROLOGICAL MARKERS

丙型肝炎病毒（HCV）抗体的存在是 既往和/或持续暴露于HCV感染。 抗体存在， 然而，在所有情况下，可能无法准确地表明血液是否 捐赠含有HCV，具有潜在传染性。 HCV-RNA水平 在血清和肝脏中，通常似乎与疾病活动平行， 表现为血清丙氨酸氨基转移酶（ALT）水平升高。 在 这项研究，HCV的出现频率和总体一致性， 使用PCR检测供体血清中的RNA，使用ELISA和RIBA II检测抗体， 进行。

The presence of antibodies to hepatitis C virus (HCV) is evidence of prior and/or ongoing exposure to HCV infection. Antibody presence, however, might not, in all cases, accurately indicate whether a blood donation contains HCV and is potentially infectious. Levels of HCV-RNA in serum and liver, in general, appear to parallel disease activity, as indicated by increased serum alanine aminotransferase (ALT) levels. In this study, the frequency and overall concordance of appearance of HCV- RNA, using PCR, and antibody, using ELISA and RIBA II, in donor sera will be undertaken.