Deciphering Signalling Pathways Regulating Iron Homeostasis

铁超载和贫血是影响人类的两个最严重的健康问题。了解身体如何调节铁水平是我们理解这些疾病和未来新疗法发展的关键。这项研究旨在了解肝脏中产生的一种叫做hepcidin的激素是如何被调节的，这种激素可以维持铁的平衡。这项研究可能会导致新的治疗方法，旨在纠正铁超载或贫血条件下的铁平衡。

Iron overload and anaemia are two of the most significant health problems affecting humans. Understanding how the body regulates iron levels is key to our understanding of these disorders and to the future development of new therapies. This research is aimed at understanding how a hormone produced in the liver called hepcidin that maintains iron balance is regulated. This research may lead to novel therapies aimed at correcting the iron balance in conditions of iron overload or anaemia.