THE POPULATION GENETICS OF TRANSPOSABLE ELEMENTS

这个项目的主要目标是研究大熊猫的种群生物学。 以果蝇为研究对象的可转座遗传元件(基因组的寄生虫) 与定量理论分析相结合的模型体系。 在此期间，研究集中在两个主题上：1)什么是 包含转座元件数量的主要机制是什么？和2) 是在元素的副本之间观察到的进化多样性 DNA序列水平与动力学的定量模型一致 自然种群中的元素？新基因的克隆及DNA测序 来自样本个体的转座元件Hobo的拷贝， 种群和物种的数量正在增加。遗传学和分子生物学 不对等互换引起的自发删除的特点 正在进行中。杂合度对不等异交率的影响 正在接受调查。

The main goal of this project is to study the population biology of transposable genetic elements (parasites of the genome) using Drosophila as a model system in conjunction with quantitative theoretical analysis. During this period, the research has focused on two topics: 1) What is the primary mechanism containing the numbers of transposable elements? and 2) Is the evolutionary diversity observed between copies of elements at the DNA sequence level consistent with quantitative models of the dynamics of the elements in natural populations? The cloning and DNA sequencing of copies of the transposable element hobo from sampled individuals, populations and species is ongoing. The genetic and molecular characteristics of spontaneous deletions arising from unequal crossing over is ongoing. The role of heterozygosity on the rate of unequal crossing over is under investigation.