PREDICTIVE VALUE OF THE EEG IN FEBRILE SEIZURES

这项基于人群的研究将评估EEG作为一种 癫痫复发的预测因子， 单纯性热性惊厥报告的结局为热性惊厥复发 和无热性惊厥的发生。脑电图模式的演变 描述，并且模式将与临床结果相关。的 临床研究正在南斯拉夫的斯科普里儿科医院进行。 斯科普里大学诊所。 该研究于1982财政年度开始，最后的随访将于2009年完成。 1991财政年度。患者招募于1984年12月完成， 约400例发热性惊厥患者，既往无复杂或 多次癫痫发作，EEG正常或非特异性异常， 登记入组研究并开始研究方案和随访。一个 另外300名具有特定异常EEG的患者被输入， 基线信息和后续行动。数据编辑和文件创建是 继续。经过现场审查访问，确定， 临床中心需要额外的努力来收集数据， 没有回访的患者和没有回访的患者 研究入组后24个月的访视。这将有助于研究 热性惊厥的长期复发，脑电图的变化，以及 脑电图对热性惊厥的诊断价值。延长的后续行动 目前正在努力。基线脑电图的统计学分析及其意义 与儿童和家庭特征以及临床特征的相关性 已经完成了扣押的特点，并已将手稿 提交出版。主文件，包括所有后续数据 所有患者的访视应于1991财政年度完成，届时 将进行进一步分析。

This population based study will evaluate the significance of the EEG as a predictor for recurrence of seizures in those children who have had a simple febrile convulsion. Outcomes reported are febrile seizure recurrence and afebrile seizure occurrence. The evolution of the EEG pattern will be described, and patterns will be correlated with the clinical outcome. The clinical study is being carried out in Skopje, Yugoslavia, at the Pediatric Clinic of the University of Skopje. The study began in FY 1982 and final follow-up visits will be completed in FY 1991. Patient accrual was completed in December, 1984, by which time approximately 400 patients with a febrile seizure, no prior complex or multiple seizures and with a normal or nonspecific abnormal EEG, were registered into the study and began the study protocol and follow-up. An additional 300 patients with a specific abnormal EEG were entered for baseline information and follow-up. Data editing and file creation are continuing. After an on-site review visit, it was determined that additional efforts by the clinical center were needed to collect data from those patients lacking a return visit and those who did not have return visits after 24 months following study entry. This will facilitate study of long-term recurrence of febrile seizures, change in EEG, and the predictive qualities of EEG for febrile seizure occurrence. The extended follow-up effort is now in progress. Statistical analysis of baseline EEG and its association with characteristics of the child and family and the clinical characteristics of the seizure has been completed and a manuscript has been submitted for publication. The master file, including follow-up data at all visits for all patients, should be completed in FY 1991, at which time further analyses will be undertaken.