COEXISTENCE OF PEPTIDES AND NEUROTRANSMITTERS

桥脑背侧被盖神经元的区域分布 采用原位杂交技术检测胆囊收缩素（CCK）mRNA 杂交组织化学技术。神经元的分布 在三叉神经运动核内观察到含有CCK mRNA的神经元 神经是一个区域，尚未显示含有CCK， 免疫细胞化学方法。此外，CCK mRNA在尾侧 中缝背核与先前相关的部分 免疫细胞化学观察。胆囊收缩素mRNA的存在， 胆碱能运动三叉神经核表明，这些细胞表达 CCK基因在以往的免疫细胞化学研究中未被发现。 提示CCK可能对肌肉收缩有影响 在三叉神经神经支配的部位（例如，咀嚼肌）。

The regional distribution of dorsal pontine tegmental neurons expressing cholecystokinin (CCK) messenger RNA (mRNA) was examined using in situ hybridization histochemical techniques. A distribution of neurons containing CCK mRNA was observed in the motor nucleus of the trigeminal nerve a region which has not been shown to contain CCK by immunocytochemical means. In addition, CCK mRNA was seen in the caudal portion of the dorsal raphe nucleus which correlates with prior immunocytochemical observations. The presence of CCK mRNA in the cholinergic motor trigeminal nucleus suggests that these cells express the CCK gene which have gone undetected in previous immunocytochemical studies. It is also suggested that CCK may have an influence on muscular contraction at sites of trigeminal nerve innervation (e.g., muscles of mastication).