FIBER OPTIC PROBES

需要一个合适的装置来直接测量氧气 临床和组织中血液和组织的分压(PO2) 研究应用。目前可用的测量方法 PO2缺乏方便性、可靠性、速度和对许多人的适用性 感兴趣的情况。开发电子传感器的努力已经 不是很成功。希望有一个非常小的PO2 可插入血管或组织的传感器 干扰小，这将提供即时血氧监测 无论是短时间还是长时间。一种光纤传感器 是这一应用的理想选择，具有生理上的优势 使用，体积非常小，灵活，安全，成本低。一个 根据PO2传感器的工作原理，研制了PO2传感器 荧光被氧猝灭。该传感器的可行性 并在实际应用中取得了令人满意的效果 前几年的体外和体内试验。国际贸易组织的发展 传感器作为针状探头已经实现。

A suitable device is needed for the direct measurement of oxygen partial pressure (pO2) in blood and tissue for both clinical and research applications. Methods currently available for measuring pO2 lack convenience, reliability, speed, and applicability to many situations of interest. Efforts to develop electrical sensors have not been successful. It is desirable to have a very small pO2 sensor which can be inserted into a blood vessel or tissue with little disturbance, that will provide instantaneous pO2 monitoring for either short or extended periods of time. A fiber-optic sensor is ideal for this application, with the advantage, for physiological use, of very small size and flexibility, safety, and low cost. A pO2 sensor has been developed, based upon the principle of fluorescence quenching by oxygen. The feasibility of the sensor and its satisfactory performance have been demonstrated in in vitro and in vivo tests in preceding years. The development of the sensor as a needle probe has been accomplished.