ABNORMAL ESOPHAGEAL MOTILITY IN PATIENTS WITH LIMITED CORONARY FLOW RESERVE

胸痛患者的胸痛症状，尽管 血管造影正常的冠状动脉包括异常的冠状动脉血流 储备和食管动力障碍。 为了确定的频率 这类患者的心脏与食管功能异常，43 尽管心外膜冠状动脉正常但仍有胸痛的患者 在以心率起搏期间测量冠状动脉阻力 麦角新碱0.5-0.3 mg静脉注射后，心率为150， 潘生丁0.5- 0.75mg/kg静注后，再用生理盐水灌胃。 那些患有 对麦角新碱的流动储备的动态限制和有限流动储备 潘生丁治疗后食管动力障碍的患病率更高 对麦角新碱没有血管收缩反应的患者， 服用潘生丁后血流储备正常 的高患病率 食管动力学受限患者的食管动力异常 冠状动脉血流储备表明，这种综合征可能是一种 平滑肌反应性的普遍异常。

Explanations for chest pain in patients with chest pain, despite angiographically normal coronary arteries include abnormal coronary flow reserve and esophageal motility disorders. To ascertain the frequency of cardiac versus esophageal functional abnormalities in such patients, 43 patients with chest pain despite normal epicardial coronary arteries underwent measurement of coronary resistance during pacing at a heart rate of 150, heart rate of 150 after ergonovine, 0.5-0.3 mg intravenously and after dipyridamole 0.5-0.75 mg/kg intravenously. Those patients who had dynamic limitation in flow reserve to ergonovine and limited flow reserve after dipyridamole had a higher prevalence of esophageal motility disorders than those patients who had no vasoconstrictor response to ergonovine and had a normal flow reserve after dipyridamole. The high prevalence of abnormal esophageal motility in patients with dynamic limitation in coronary flow reserve suggests that this syndrome may be part of a generalized abnormality of smooth muscle rectivity.