ULTRASOUND TECHNIQUE FOR PROSTATE THERMAL THERAPY

一种用于高度受控的热和/或烧蚀的系统和技术 提出了前列腺癌的治疗方法。经尿道和迷你电切术 带有相关治疗的植入式超声治疗敷贴器 计划和控制系统被用来实现最佳治疗 在前列腺内分娩。声场整形和 治疗计划用于实现对整个腺体的治疗， 或腺体的亚区。这一方法提供了优惠 治疗起源于外周区域的癌症，但可以 针对源自其他区域的疾病进行了优化。适当的 探头的组合和位置使可控和 可动态调整的治疗区域。总体目标是 使用以下技术组合开发微创技术 经直肠和2至3个微型超声针探头 有效治疗，同时保留直肠、膀胱和其他 正常的关键组织结构。 建议的商业应用： 这项研究的结果可能会立即对 治疗前列腺癌的毒副作用和发病率较低。一个 存在大量符合条件的患者，包括复发患者 放射治疗后，那些有包膜外延长者注意到 在根治性前列腺切除术后，以及那些不能耐受或 选择不进行开放手术。

A system and technique for highly controlled thermal and/or ablative therapy of the prostate is proposed. Transurethral and miniature implantable ultrasound therapy applicators, with associated treatment planning and control systems are used to achieve optimal therapy delivery within the prostate gland. Acoustic field shaping and treatment planning are used to achieve treatment of the entire gland, or subregions of the gland. This approach provides for preferential treatment of cancers originating in the peripheral zone, yet can be optimized for disease originating in other zones. The appropriate combinations and positions of probes localize controllable and dynamically adjustable treatment zones. The overall objective is to develop minimally invasive techniques using a combination of transrectal and 2 to 3 miniature ultrasound needle probes for efficacious therapy while sparing the rectum, bladder, and other normal critical tissue structures. PROPOSED COMMERCIAL APPLICATIONS: The outcome of this research could be of immediate benefit in the treatment of prostate cancer with fewer toxicities and morbidity. A large number of eligible patients exists, including those who recur after radiation, those who have extracapsular extension noted following radical prostatectomy, and those who cannot tolerate or select not to have open surgery.