DESIGN/DEVELOPMENT OF HAP BONE SCAFFOLDS

由于创伤性和非创伤性事件而导致的损伤和/或丢失的骨的置换是医学上相当感兴趣的问题。生物陶瓷由于其无毒性、生物相容性和可控制的吸收而被用作骨移植物。本研究旨在建立具有独特设计的多孔羟基磷灰石（RAP）陶瓷结构的可行性，这些结构是其他可用方法无法制造的。这项工作将提供陶瓷植入物的机械性能与孔隙率相关参数之间的关系。建议的商业应用：使用FDC技术开发多孔生物陶瓷材料将为生产具有高机械强度、生物相容性和生物降解的骨移植部件提供机会。这一过程可以对硬组织修复和替换领域产生重大影响，这是一个全球年营业额为23亿美元的行业，预计年增长率为7-12%。

The replacement of damaged and/or lost bone due to traumatic and non- traumatic events is of considerable interest in medicine. Bioceramics have been used as bone grafts due to their non-toxic nature, biocompatibility, and controlled resorption. This research aims to establish the feasibility of fabricating porous hydroxyapatite (RAP) ceramic structures with unique designs that cannot be made by other available methods. This work will provide a relationship between the mechanical properties of the ceramic implants and the parameters associated with porosity. PROPOSED COMMERCIAL APPLICATION: The development of porous bioceramic materials using FDC technology will provide an opportunity to produce bone graft components with high mechanical strength, biocompatibility, and biodegradation. This process can have a significant impact in the field hard tissue repair and replacement, an industry with a worldwide annual turnover of $2.3 billion and a projected growth rate of 7-12% per year.