高血压表型的统计遗传学分析--家族研究-猫眼课题宝

高血压表型的统计遗传学分析--家族研究

批准号：

6109034

负责人：

A F WILSON

金额：

$0.0万

依托单位：

NATIONAL HUMAN GENOME RESEARCH INSTITUTE

依托单位国家：

美国

项目类别：

财政年份：

资助国家：

美国

项目状态：

未结题

起止时间：

至

来源：

https://reporter.nih.gov/project-details/6109034

关键词：

blood pressure clinical research computer simulation familial hypertension family genetics gene expression genetic polymorphism genotype human subject hypertension linkage mapping neuroeffector phenotype statistics /biometry

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中文摘要

翻译

高血压相关特征的家庭数据超过

英文摘要

Family data on traits related to hypertension on over 300 individuals have been collected by Drs. O'Connor and Parmer at UCSD. The objective of the project is to investigate the variation in traits related to aspects of the sympatheic neuroeffector juction and ultimately in changes in blood pressure and hypertension, and to attempt to determine whether genetic components are responsible, at least in part, for this variation. Computer simulation studies have been done to determine the power of the sample to detect linkage. Genotyping for the project has been approved by the Center for Inherited Disease Research Access Committee. The collection of additional phenotyping information is conditional on obtaining additional NIH funding.

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