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GROWTH HORMONE RELEASING HORMONE ANTAGONIST ON GH RELEASE IN ACROMEGALY

GROWTH HORMONE RELEASING HORMONE ANTAGONIST ON GH RELEASE IN ACROMEGALY
生长激素释放激素拮抗剂对肢端肥大症患者 GH 释放的影响
批准号：
6113352
负责人：
CRAIG A JAFFE
金额：
$0.02万
依托单位：
UNIVERSITY OF MICHIGAN AT ANN ARBOR
依托单位国家：
美国
项目类别：
财政年份：
1998
资助国家：
美国
项目状态：
已结题
起止时间：
1998-12-01 至 1999-11-30
来源：
https://reporter.nih.gov/project-details/6113352
关键词：
acromegaly aging clinical research growth hormone releasing hormone hormone regulation /control mechanism human subject hypothalamus secretion somatotropin

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中文摘要
翻译
本研究的目的是确定内源性生长激素释放激素(GHRH)在调节男性和女性夜间、基础和药物刺激的GH分泌中的作用。GHRH的分泌与年龄有关，肢端肥大症的GH高分泌是由下丘脑GHRH驱动的假说也在研究中。
英文摘要
The purpose of the study is to determine the role of endogenous growth hormone (GH)-releasing hormone (GHRH) in the regulation of nocturnal, basal and pharmacologically stimulated GH secretion in men and women. The hypotheses that GHRH secretion is age related and that GH hypersecretion in acromegaly is driven by hypothalamic GHRH are also being investigated.
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