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MYCOPHENOLATE MOFETIL AND PLACEBO IN PATIENTS WITH RHEUMATOID ARTHRITIS

MYCOPHENOLATE MOFETIL AND PLACEBO IN PATIENTS WITH RHEUMATOID ARTHRITIS
霉酚酸酯和安慰剂治疗类风湿性关节炎患者
批准号：
6219479
负责人：
NANCY L LANE
金额：
$0.06万
依托单位：
UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
依托单位国家：
美国
项目类别：
财政年份：
1998
资助国家：
美国
项目状态：
已结题
起止时间：
1998-12-01 至 1999-11-30
来源：
https://reporter.nih.gov/project-details/6219479
关键词：
antiarthritic agent antirheumatic agents clinical research drug screening /evaluation human subject human therapy evaluation mycophenolic acid quality of life skeletal disorder chemotherapy

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中文摘要
翻译
本项目的目的是：（1）证明霉酚酸酯（MMG）与安慰剂相比在缓解率方面的有效性（根据美国流变学学会20项标准评估）;和（2）证明MMF在改善肿胀关节计数、压痛关节计数、医生对疾病活动性的总体评估、患者对疾病活动性的总体评估患者疼痛评估和生活质量评估。
英文摘要
The aims of this project are to: (1) demonstrate the efficacy of mycophenolate mofetil (MMG) compared to placebo in the responder rate as assessed by the American College of Rheumatology 20 criteria; and (2) demonstrate the efficacy of MMF in improvement in swollen joint count, tender joint count, physicianUs global assessment of disease activity, patient Us global assessment of disease activity, patientUs assessment of pain, and quality of life assessments.
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SAFETY & EFFICACY OF RO 32 35555 IN ARTHRITIS
MYCOPHENOLATE MOFETIL AND PLACEBO IN PATIENTS WITH RHEUMATOID ARTHRITIS
DOSE RANGING STUDY OF CI-1004 IN PATIENTS WITH OSTEOARTHRITIS
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