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PHARMACOLOGY OF ANTIRHEUMATIC AGENTS

PHARMACOLOGY OF ANTIRHEUMATIC AGENTS
抗风湿药的药理学
批准号：
6115762
负责人：
BRUCE Neil CRONSTEIN
金额：
$2.1万
依托单位：
NEW YORK UNIVERSITY SCHOOL OF MEDICINE
依托单位国家：
美国
项目类别：
财政年份：
1998
资助国家：
美国
项目状态：
已结题
起止时间：
1998-12-01 至 1999-11-30
来源：
https://reporter.nih.gov/project-details/6115762
关键词：
adenosine antiinflammatory agents biological signal transduction clinical research clinical trials drug screening /evaluation enzyme linked immunosorbent assay human subject human therapy evaluation methotrexate northern blottings nucleic acid chemical synthesis polymerase chain reaction rheumatoid arthritis skeletal disorder chemotherapy skeletal pharmacology sulfanilamides

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中文摘要
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英文摘要
This study demonstrates that in in vivo models and patients with rheumatoid arthritis the effects of antiinflammatory drugs, specifically methotrexate and sulfasalzine, are due to their capacity to increase extracellular adenosine. The investigators have concluded that signal transduction of adenosine proceeds by a novel pathway. The lab was used for ELISA, oligonucleotide synthesis, PCR and recombinant DNA techniques.
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Clinical and Translational Science Award
Engineering Personalized Devices for Craniomaxillofacial Defects
  • 批准号：
    10116988
  • 项目类别：
  • 资助金额：
    $38.58万
  • 财政年份：
    2019
  • 负责人：
    BRUCE Neil CRONSTEIN
  • 依托单位：
    NEW YORK UNIVERSITY
Clinical and Translational Science Award
Clinical and Translational Science Award
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