CRYSTALLOGRAPHIC REFINEMENT OF A HEMOLYSIN, HEPTAMERIC TRANSMEMBRANE PORE

DNA的六套基本基因和三到四个刺激基因 已在两种杆状病毒中发现复制：AcMNPV和 OpMNPV。此外，这两种病毒都有多种来源的DNA。 以相对较短的起始点为组的复制 回文结构和更复杂的更大的起源 定义得很清楚。尽管信息如此丰富，但有限的信息 关于编码复制功能的可用 因此，这些蛋白质组将接受分析以确定 可能的主题、使用不同参数的数据库搜索(PAM)、 多个序列比对等。此外，搜索同源性 使用其他病毒的DNA复制蛋白，并使用Short搜索 将对AcMNPV的整个基因组进行保守模式 (134KB)。分析起源结构，寻找共性 在不同的复制起源之间。

Sets of six essential and three to four stimulating genes for DNA replication have been identified in 2 Baculoviruses: AcMNPV and OpMNPV. In addition, both viruses have multiple origins of DNA replication that fall into groups of relative short origins with a Palindromic structure and larger origins that are more complex and not well-defined. Despite this wealth of information, limite information about the function of the encoded replication faction is available Therefore, these sets of proteins will be subjected to analyses for possible motifs, database searches with different parameters (PAM's), multiple sequence alignments, etc. Furthermore, searches for homology with DNA replication proteins of other viruses and searches with short conserved patterns will be carried out with the entire AcMNPV genome (134kb). Analyses of origin structures, search for commonalities among different origins of replication.