CLINICAL RESEARCH ON AIDS TRAINING GRANT

描述（改编自应用程序）：旨在开发和评估有效治疗和预防艾滋病毒/艾滋病的干预措施的研究继续提出统计方面的挑战。研究人员建议继续进行一项正在进行的生物统计学艾滋病培训计划，该计划将支持四名博士生和两名博士后。该培训计划旨在提供1)生物统计理论和应用基础方面的良好培训；2)通过特殊课程、艾滋病生物学项目、系列研讨会和期刊俱乐部，以及与其他学科艾滋病学员的互动，为艾滋病问题提供学术丰富的机会；3)与知名艾滋病研究人员合作，开展艾滋病临床、流行病学和方法生物统计研究。该计划将以生物统计系以及公共卫生和社区医学学院和医学院的其他系为中心。培训方案的学术部分将强调生物统计理论和应用的基础，以及艾滋病毒/艾滋病的生物学和流行病学方面的具体课程。受训者所修的大多数正式课程将由生物统计处、统计处和流行病学处的人员讲授。现有课程还将补充关于艾滋病研究方法问题和性传播疾病/艾滋病研究生物统计咨询的新课程。受训人员还将定期参加一系列每周生物统计学研讨会、每月一次艾滋病临床会议和每两周一次的艾滋病杂志俱乐部。除了参与一个或多个临床研究项目外，培训计划的研究部分将侧重于正在进行的生物统计方法学研究的合作。临床研究项目将从HIVNET统计中心、华盛顿大学艾滋病研究中心、华盛顿大学国际艾滋病研究和培训计划以及区域生物技术公司正在进行的研究中确定。积极参与艾滋病研究的生物统计学系教员将担任导师，帮助学员整合必要的知识和技能，为艾滋病临床研究的多学科活动做出贡献。

DESCRIPTION (Adapted from the application): Research aimed at developing and evaluating interventions to effectively treat and prevent HIV/AIDS continues to present statistical challenges. The investigators propose to continue an ongoing Biostatistical AIDS Training Program which will support four predoctoral and two postdoctoral students. The training program proposes to provide 1) sound training in the foundations of biostatistical theory and applications, 2) opportunities for academic enrichment in AIDS issues through special courses, AIDS biology projects, seminar series and journal clubs, and interactions with AIDS trainees from other disciplines, and 3) collaboration with established AIDS researchers in the conduct of clinical, epidemiological and methodologic biostatistical research in AIDS. The program will be centered in the Department of Biostatistics, as well as, other departments in the School of Public Health and Community Medicine, and the School of Medicine. The academic component of the training program will emphasize the foundations of biostatistical theory and applications, as well as specific coursework in the biology and epidemiology of HIV/AIDS disease. Most of the formal courses to be taken by the trainees will be taught by members of the Biostatistics, Statistics and Epidemiology Departments. The existing curriculum will also be supplemented by new courses on methodologic issues in AIDS research and biostatistical consulting in STD/AIDS research. The trainees will also attend regular series of weekly biostatistics seminars, a monthly AIDS Clinical Conference, and biweekly AIDS journal club. The research component of the training program will focus on collaboration in ongoing biostatistical methodology research in addition to involvement in one or more clinical research projects. The clinical research projects will be identified from ongoing studies in the HIVNET Statistical Center, the University of Washington Center for AIDS Research, the University of Washington International AIDS Research and Training Program, and regional biotechnology firms. Faculty in the Biostatistics Department actively participating in AIDS research will serve as preceptors and help the trainees integrate the knowledge and skills necessary to contribute to the multidisciplinary activity of clinical research in AIDS.