Development of Reversible Inhibitors of Factor XIa

血液通常会因受伤而凝块，但不需要的凝块会导致血栓形成，并导致中风和心脏病。现有治疗血栓形成的药物存在一些缺陷，比如侵入性监测、与饮食和其他药物的相互作用，以及出血并发症。显然需要新药。我们的专家组研究人员将发现新的抗血栓化合物的基础上，我们以前鉴定的天然产品具有抗凝血特性。

Blood usually clots in response to injury, but unwanted clots can cause thrombosis, as well as leading to stroke and heart disease. Existing drugs to treat thrombosis suffer from drawbacks such as invasive monitoring, interaction with diet and other medicines, and bleeding complications. New drugs are clearly needed. Our expert group of researchers will discover new anti-thrombotic compounds based upon our previous identification of natural products with anticoagulant properties.