INTESTINAL LIPID ABSORPTION, METABOLISM AND TRANSPORT

描述（改编自应用程序） 该申请要求部分资金用于FASEB夏季研究 肠脂质吸收、代谢和转运会议即将召开 2000年7月29日至2000年8月3日在佛蒙特州萨克顿河的佛蒙特学院。 这将是关于这一主题的第四次此类会议， 在1997年的夏天。该会议的独特之处在于其高度多学科性 接近主题。因此，我们将召集高年级和低年级学生 在营养学，生理学， 生物化学、蛋白质化学、细胞和分子生物学以及发育 生物学，以解决脂质代谢的最新进展，因为它们涉及 肠子该格式包括八个主要的口头会议（上午五个和三个 PM）。约有40名受邀发言者初步同意参加。 每个会议的主题都集中在活跃的研究领域：1）甾醇 吸收; 2）脂质代谢; 3）脂质结合/转运蛋白; 4） 脂质代谢的发育调节; 5）胆汁的形成和分泌; 6)肠脂肪酶; 7）肠载脂蛋白;和8）脂质信号转导 胃肠道每位演讲者将有20分钟的时间介绍他们最近的 和未发表的工作，将集中在他们的领域的重大进展， 专业知识，并确定在我们的知识中仍然存在的缺陷， 科学每次演讲后将有至少10分钟的 问题和讨论。将鼓励所有与会者张贴海报， 海报展示会将于每日下午稍后时间举行。用餐时间和 自由的下午将允许与会者之间进行积极的对话， 会议此外，一个晚上的主题演讲将由博士发表。 贝弗利·佩根是杰克逊实验室的著名分子遗传学家， 他将讨论胆汁形成的分子遗传学。前三 1990年、1994年和1997年的会议非常成功，与会者 同意应计划在2000年再举行一次会议。高 前三次会议的出席情况证明， 这个领域的科学界。鉴于快速的发展， 自上次会议以来，我们期望2000年会议应 在初级调查员和更多人之间促进令人兴奋的开放交流 建立科学家，希望能导致新的合作， 补充专业知识，以进一步这一重要的研究领域。

DESCRIPTION (adapted from the application) This application requests partial funding for a FASEB Summer Research Conference on Intestinal Lipid Absorption, Metabolism, and Transport to be held July 29, 2000-August 3, 2000 at the Vermont Academy, Saxtons River, Vermont. This will be the fourth such conference on this theme, the last one being held in the summer of 1997. The conference is unique in its highly multidisciplinary approach to the topic. Thus, we will bring together senior and junior investigators with expertise in the areas of nutrition, physiology, biochemistry, protein chemistry, cell and molecular biology, and developmental biology, to address recent advances in lipid metabolism as they relate to the intestine. The format consists of eight major oral sessions (five AM and three PM). Approximately 40 invited speakers have tentatively agreed to participate. The topics of each session are all focused on active research areas: 1) Sterol absorption; 2) Lipid Metabolism; 3) Lipid Binding/Transport Proteins; 4) Developmental Regulation of Lipid Metabolism; 5) Bile Formation and Secretion; 6) Intestinal Lipases; 7) Intestinal Apolipoproteins; and 8) Lipid Signaling in the GI tract. Each speaker will have 20 minutes to present their most recent and unpublished work that will focus on major advances in their field of expertise, and on identifying deficits that remain in our knowledge of the science. Each presentation will be followed by at least 10 minutes for questions and discussion. Posters will be encouraged from all attendees, and poster sessions will be held daily in the late afternoon. The mealtimes and free afternoons will allow for active dialogue among participants of the conference. In addition, an evening Keynote Address will be delivered by Dr. Beverly Paigen, a renowned molecular geneticist at the Jackson Laboratories, who will discuss the molecular genetics of bile formation. The three previous conferences in 1990, 1994, and 1997 were very successful, with the participants agreeing that another conference should be planned for the year 2000. The high attendance at all three of the previous meetings attests to the interest in this field by the scientific community. Given the rapid developments that have occurred since the last conference, we expect that the 2000 conference should foster an exciting and open exchange among junior investigators and more established scientists that will hopefully result in new collaborations with complementary expertise to further this Important field of study.