CLINICAL RESEARCH ON AIDS TRAINING GRANT

描述（改编自应用程序）：旨在开发和评估有效治疗和预防艾滋病毒/艾滋病的干预措施的研究继续提出统计挑战。研究人员建议继续进行一项正在进行的生物统计艾滋病培训计划，该计划将支持四名博士前和两名博士后学生。 该培训计划建议提供1）生物统计理论和应用基础方面的良好培训，2）通过特殊课程，艾滋病生物学项目，系列研讨会和期刊俱乐部，以及与其他学科的艾滋病学员的互动，为艾滋病问题提供学术丰富的机会，以及3）与知名艾滋病研究人员合作进行临床，艾滋病流行病学和方法学生物统计学研究。该计划将集中在生物统计学系，以及公共卫生和社区医学学院的其他部门，以及医学院。培训计划的学术部分将强调生物统计理论和应用的基础，以及艾滋病毒/艾滋病疾病的生物学和流行病学的具体课程。 受训人员将参加的大部分正式课程将由生物统计学、统计学和流行病学系的成员讲授。 现有的课程还将由关于艾滋病研究方法问题和性病/艾滋病研究生物统计咨询的新课程加以补充。 学员还将参加每周一次的定期生物统计研讨会、每月一次的艾滋病临床会议和每两周一次的艾滋病杂志俱乐部。 培训计划的研究部分将侧重于正在进行的生物统计方法学研究的合作，以及参与一个或多个临床研究项目。 临床研究项目将从艾滋病毒网络统计中心、华盛顿大学艾滋病研究中心、华盛顿大学国际艾滋病研究和培训计划以及区域生物技术公司正在进行的研究中确定。 积极参与艾滋病研究的生物统计系教师将担任导师，帮助学员整合必要的知识和技能，为艾滋病临床研究的多学科活动做出贡献。

DESCRIPTION (Adapted from the application): Research aimed at developing and evaluating interventions to effectively treat and prevent HIV/AIDS continues to present statistical challenges. The investigators propose to continue an ongoing Biostatistical AIDS Training Program which will support four predoctoral and two postdoctoral students. The training program proposes to provide 1) sound training in the foundations of biostatistical theory and applications, 2) opportunities for academic enrichment in AIDS issues through special courses, AIDS biology projects, seminar series and journal clubs, and interactions with AIDS trainees from other disciplines, and 3) collaboration with established AIDS researchers in the conduct of clinical, epidemiological and methodologic biostatistical research in AIDS. The program will be centered in the Department of Biostatistics, as well as, other departments in the School of Public Health and Community Medicine, and the School of Medicine. The academic component of the training program will emphasize the foundations of biostatistical theory and applications, as well as specific coursework in the biology and epidemiology of HIV/AIDS disease. Most of the formal courses to be taken by the trainees will be taught by members of the Biostatistics, Statistics and Epidemiology Departments. The existing curriculum will also be supplemented by new courses on methodologic issues in AIDS research and biostatistical consulting in STD/AIDS research. The trainees will also attend regular series of weekly biostatistics seminars, a monthly AIDS Clinical Conference, and biweekly AIDS journal club. The research component of the training program will focus on collaboration in ongoing biostatistical methodology research in addition to involvement in one or more clinical research projects. The clinical research projects will be identified from ongoing studies in the HIVNET Statistical Center, the University of Washington Center for AIDS Research, the University of Washington International AIDS Research and Training Program, and regional biotechnology firms. Faculty in the Biostatistics Department actively participating in AIDS research will serve as preceptors and help the trainees integrate the knowledge and skills necessary to contribute to the multidisciplinary activity of clinical research in AIDS.