PRE- AND POSTDOCTORAL TRAINING IN BIOCHEMISTRY OF AGING

描述：为BUSM的六名博士生和六名博士后的机构培训计划，要求五年的持续支持总额为1,645,548美元的直接费用。培训的重点是衰老的细胞和分子生物学，特别强调衰老的生物化学。该应用程序将合并两个以前独立的NIA资助的培训项目，分别位于生物化学系和皮肤学系，将包括24名研究兴趣为神经生物学、细胞生长、细胞信号、结缔组织生物化学和遗传学的教员。它要求继续现有的6个博士前和6个博士后实习名额。两个博士后名额目前位于皮肤科培训计划，将纳入本计划。培训包括在衰老的临床和流行病学方面的框架内，在衰老的细胞和分子生物学领域开展正式课程、研讨会、期刊俱乐部和个人研究项目。我们的目标是培养这些领域的博士和医学博士。毕业后将从事老年学研究的独立调查员。

DESCRIPTION: Five years of continuing support totaling $1,645,548 in direct costs are requested for an institutional training program at BUSM for six predoctoral and six postdoctoral fellows. The training focuses on the cellular and molecular biology of aging, with particular emphasis on the biochemistry of aging. This application will merge two previously independent NIA sponsored training programs located in the Departments of Biochemistry and Dermatology, and will include 24 faculty members with research interests in neurobiology, cell growth, cell signaling, connective tissue biochemistry, and genetics. It requests continuation of the combined current number of trainee slots of six predoctoral and six postdoctoral positions. Two of the postdoctoral slots are presently located in the Department of Dermatology training program which will be incorporated into this program. The training includes formal course work, seminars, journal clubs and individual research projects in the areas of cell and molecular biology of aging within a framework of the clinical and epidemiologic aspects of aging. The goal is to train individuals in these areas for both the Ph.D. and M.D./Ph.D. degrees who will later pursue careers as independent investigators in gerontological research.