BRAIN INFORMATION MANAGEMENT SYSTEM
BRAIN INFORMATION MANAGEMENT SYSTEM
批准号:
6219704
负责人:
Douglas M. BOWDEN
金额:
$7.46万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
1999
资助国家:
美国
项目状态:
已结题
起止时间:
1999-05-01 至 2000-04-30
中文摘要
将大脑的新信息与
现有的知识正呈指数级增长。 该项目涉及
大脑信息管理系统(Brain Information Management System,BIMS)
让科学家们可以随时获得这两种信息,
临床医生和学生在万维网上。因为大多数知识
关于人类大脑的研究是基于对非人类灵长类动物的研究,
信息被编入计算机化的猕猴模板地图集
我们去年在网上建立的大脑。 1998年,我们
通过添加NeuroNames(一个大脑词汇表)来增强网站
在我们的实验室开发的结构,并纳入
国家医学图书馆统一医学语言系统。
NeuroNames为神经科学带来了新的标准化水平
通过定义7,000多个经典的神经解剖学名称,
一套标准的大脑初级结构。 这些是
在非人类灵长类动物中,通过与模板地图集的链接来说明,
通过链接到另一个网站,
部 华盛顿大学的生物结构研究所。
通过应用以下技术,进一步扩展了建筑信息管理系统:
地理信息系统(GIS)软件管理图像
关于大脑的信息。 约1500幅插图,
文献被映射到地图集中的模板,
许多神经科学数据的标准格式,
例如,在一个实施例中,特定种类的神经细胞,特定基因的区域
表达,以及电刺激,化学治疗
或病变影响行为的特定方面。 此外,本发明还提供了一种方法,
用于绘图的原始数据是在显微镜研究中产生的。
1型腺苷酸环化酶在大鼠海马中的分布
猕猴。 资助NIH拨款RR00166和LM/OD 06243。 Bowden,D. M.,
罗伯逊,J.E.,Dubach,J.,Martin,R.F. 03 The Dog(1998)
Atlas/Brain Information; Neurosciences Div.,区域灵长类研究
华盛顿大学中心。 (网址
http://rprcsgi.rprc.washington.edu/neuronames/;内容等同于
500页文本)Robertson,J.E.,Martin,R.F. Dubach,J.G.和鲍登,
D.M. NeuroNames和模板图谱。 WebNet '98世界会议
1998年11月7日至12日在佛罗里达州奥兰多市举行的WWW、因特网和内联网会议上发表。
(摘要)Bowden,D.M.,马丁,R. F.,罗伯逊,J.E.,和J.G.
杜巴赫 神经名称和猕猴大脑的模板图谱。 Soc.
神经科学,1998年年会。 加利福尼亚州洛杉矶。 11月7日至12日,
1998. (摘要)[该项目也在《神经科学》上报道
核心部分。]
英文摘要
The problem of integrating new information about the brain with
existing knowledge is expanding exponentially. This project addresses
the problem by creating a Brain Information Management System (BIMS)
to make both kinds of information readily available to scientists,
clinicians and students on the World Wide Web. Since most knowledge
about the human brain is based on studies of nonhuman primates, the
information is indexed to a computerized Template Atlas of the macaque
brain which we established on the Web last year. In 1998 we greatly
enhanced the website by adding NeuroNames, a glossary of brain
structures developed in our laboratory and incorporated into the
Unified Medical Language System of the National Library of Medicine.
NeuroNames brings a new level of standardization to neuroscientific
research by defining more than 7,000 classical neuroanatomical names
in terms of a standard set of primary brain structures. These are
illustrated in the nonhuman primate by links to the Template Atlas and
in the human by links to another website, the Digital Anatomist of the
Dept. of Biological Structure at the University of Washington.
Future expansion of the BIMS was furthered by application of
Geographical Information Systems (GIS) software to managing image
information about the brain. Some 1500 illustrations from the
literature were mapped to templates in the Atlas to display in a
standard format the location of many kinds of neuroscientific data,
e.g., particular kinds of nerve cell, areas of specific gene
expression, and sites where electrical stimulation, chemical treatment
or lesions influence specific aspects of behavior. In addition,
original data for mapping were generated in a microscopic study of the
distribution of type-1 adenylyl cyclase in the hippocampus of the
macaque. FUNDING NIH grants RR00166 and LM/OD 06243. Bowden, D.M.,
Robertson, J.E., Dubach, J., Martin, R.F. (1998) NeuroNames/Template
Atlas/Brain Information; Neurosciences Div., Regional Primate Research
Center, University of Washington. (Website
http://rprcsgi.rprc.washington.edu/neuronames/; contents equivalent to
500 page text) Robertson, J.E., Martin, R.F. Dubach, J.G. and Bowden,
D.M. NeuroNames and the Template Atlas. WebNet '98 World Conference
of the WWW, Internet & Intranet, Orlando, FL. November 7-12, 1998.
(Abstract) Bowden, D.M., Martin, R.F., Robertson, J.E., and J.G.
Dubach. NeuroNames and a template atlas of the macaque brain. Soc.
for Neuroscience, 1998 Ann. Meeting. Los Angeles, CA. Nov. 7-12,
1998. (Abstract) [This project was also reported in the Neuroscience
Core section.]
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
COMPREHENSIVE DIGITAL ATLAS OF MACAQUE BRAIN
-
批准号:7349348
-
项目类别:
-
资助金额:$13.2万
-
财政年份:2006
-
负责人:Douglas M. BOWDEN
-
依托单位:
Spatial Information Management Resources for Human Brain
-
批准号:7245904
-
项目类别:
-
资助金额:$30.2万
-
财政年份:2005
-
负责人:Douglas M. BOWDEN
-
依托单位:
BIOSTRUCTURE TECHNOLOGY LABORATORY (BSTL)
-
批准号:7165751
-
项目类别:
-
资助金额:$9.05万
-
财政年份:2005
-
负责人:Douglas M. BOWDEN
-
依托单位:
Spatial Information Management Resources for Human Brain
-
批准号:7038298
-
项目类别:
-
资助金额:$30.41万
-
财政年份:2005
-
负责人:Douglas M. BOWDEN
-
依托单位:
Spatial Information Management Resources for Human Brain
-
批准号:6758815
-
项目类别:
-
资助金额:$33.4万
-
财政年份:2005
-
负责人:Douglas M. BOWDEN
-
依托单位:
Comprehensive Digital Atlas of the Macaque Brain
-
批准号:7269422
-
项目类别:
-
资助金额:$52.09万
-
财政年份:2004
-
负责人:Douglas M. BOWDEN
-
依托单位:
Comprehensive Digital Atlas of the Macaque Brain
-
批准号:6803830
-
项目类别:
-
资助金额:$54.21万
-
财政年份:2004
-
负责人:Douglas M. BOWDEN
-
依托单位:
Comprehensive Digital Atlas of the Macaque Brain
-
批准号:7127222
-
项目类别:
-
资助金额:$53.19万
-
财政年份:2004
-
负责人:Douglas M. BOWDEN
-
依托单位:
Comprehensive Digital Atlas of the Macaque Brain
-
批准号:6927802
-
项目类别:
-
资助金额:$49.89万
-
财政年份:2004
-
负责人:Douglas M. BOWDEN
-
依托单位:
BIOSTRUCTURE TECHNOLOGY LABORATORY (BSTL)
-
批准号:6971648
-
项目类别:
-
资助金额:$10.07万
-
财政年份:2004
-
负责人:Douglas M. BOWDEN
-
依托单位:
BIOSTRUCTURE TECHNOLOGY LABORATORY (BSTL)
-
批准号:6940057
-
项目类别:
-
资助金额:$5.05万
-
财政年份:2003
-
负责人:Douglas M. BOWDEN
-
依托单位:
NEURAL SUBSTRATES OF LEARNING
-
批准号:6219617
-
项目类别:
-
资助金额:$5.72万
-
财政年份:1999
-
负责人:Douglas M. BOWDEN
-
依托单位:
GROOMING PREFERENCE & GENDER
-
批准号:6116362
-
项目类别:
-
资助金额:$8.67万
-
财政年份:1999
-
负责人:Douglas M. BOWDEN
-
依托单位:
COMPUTERIZED BRAIN ATLAS FOR MACACA FASCICULARIS
-
批准号:6116290
-
项目类别:
-
资助金额:$8.67万
-
财政年份:1999
-
负责人:Douglas M. BOWDEN
-
依托单位:
GROOMING PREFERENCE & GENDER
-
批准号:6219677
-
项目类别:
-
资助金额:$13.45万
-
财政年份:1999
-
负责人:Douglas M. BOWDEN
-
依托单位:
TYPE 1 ADENYLYL CYCLASE IN PRIMATE BRAIN
-
批准号:6219703
-
项目类别:
-
资助金额:$7.46万
-
财政年份:1999
-
负责人:Douglas M. BOWDEN
-
依托单位:
NEURAL SUBSTRATE OF LEARNING
-
批准号:6116291
-
项目类别:
-
资助金额:$8.67万
-
财政年份:1999
-
负责人:Douglas M. BOWDEN
-
依托单位:
BRAIN INFORMATION MANAGEMENT SYSTEM
-
批准号:6219606
-
项目类别:
-
资助金额:$5.72万
-
财政年份:1999
-
负责人:Douglas M. BOWDEN
-
依托单位:
NEURAL SUBSTRATE OF LEARNING
-
批准号:6277525
-
项目类别:
-
资助金额:$9.18万
-
财政年份:1998
-
负责人:Douglas M. BOWDEN
-
依托单位:
GROOMING PREFERENCE & GENDER
-
批准号:6277596
-
项目类别:
-
资助金额:$7.23万
-
财政年份:1998
-
负责人:Douglas M. BOWDEN
-
依托单位: