REGIONAL FATTY ACID METABOLISM IN HUMANS

这项研究的目的是确定患有和不患有糖尿病的超重女性在治疗前后一餐中的脂肪是如何被吸收和储存在体脂中的，以期达到减肥和改善与肥胖相关的健康问题的目的。对数据的分析表明，我们已经解决了我们的假设，一篇论文已经撰写并提交发表。由于芬氟拉明/芬太尼引起的心脏瓣膜疾病的问题，我们撤回了所有志愿者的这些药物。每名志愿者都在接受密切跟踪，以评估瓣膜异常的进展或消退。在本报告所述期间，没有病人活动。样品分析在生物医学质谱学核心实验室继续进行。

The purpose of this study is to determine how fat contained in a meal is absorbed and stored in body fat in overweight women with and without diabetes before and after treatment expected to result in weight loss and improvement of health problems related to obesity. Analysis of the data indicated we had addressed our hypothesis and a paper has been written and submitted for publication. Because of the problems with cardiac valvular disease induced by fenfluramine/phentermine, we withdrew all volunteers from these medications. Each volunteer is being followed closely to assess whether there is progression or regression of the valvular abnormalities. There was no patient activity during this reporting period. Sample analysis was continued in the Biomedical Mass Spectrometry Core Laboratory.