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EFFECT OF RHGH ON ENDURANCE AND CARDIOPULMONARY FUNCTION IN GH DEFICIENT ADULTS

EFFECT OF RHGH ON ENDURANCE AND CARDIOPULMONARY FUNCTION IN GH DEFICIENT ADULTS
RHGH 对 GH 缺乏成人的耐力和心肺功能的影响
批准号：
6115735
负责人：
DAVID L KLEINBERG
金额：
$2.1万
依托单位：
NEW YORK UNIVERSITY SCHOOL OF MEDICINE
依托单位国家：
美国
项目类别：
财政年份：
1998
资助国家：
美国
项目状态：
已结题
起止时间：
1998-12-01 至 1999-11-30
来源：
https://reporter.nih.gov/project-details/6115735
关键词：
adult human (21+) body composition cardiovascular function clinical research drug screening /evaluation echocardiography exercise hormone therapy human subject human therapy evaluation insulinlike growth factor physical fitness pituitary dwarfism recombinant proteins respiratory function somatotropin

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中文摘要
翻译
目的是通过超声心动图和跑步机运动试验确定长期rhGH替代对耐力、心肺功能和心脏结构的影响。DEXA身体扫描将用于评估肌肉、脂肪和骨密度。结果将与替代治疗后的GH和IGF-1水平相关。
英文摘要
The objectives are to determine the effects of long-term rhGH replacement on endurance, cardiopulmonary function and cardiac structure using echocardiography and treadmill exercise testing. DEXA body scans will be performed to assess muscle, fat mas, and bone densitometry. Outcomes will be correlated with GH and IGF-1 levels post replacement therapy.
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