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LEUCINE KINETICS OF (I-13C)LEUCINE AS AMINO ACID OR AS (I-13C)LEUCINE CASEIN

LEUCINE KINETICS OF (I-13C)LEUCINE AS AMINO ACID OR AS (I-13C)LEUCINE CASEIN
(I-13C) 亮氨酸作为氨基酸或 (I-13C) 亮氨酸酪蛋白的亮氨酸动力学
批准号:
6115562
负责人:
VERNON R YOUNG
金额:
$4.04万
依托单位国家:
美国
项目类别:
财政年份:
1998
资助国家:
美国
项目状态:
已结题
起止时间:
1998-12-01 至 1999-11-30

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中文摘要
翻译
本研究将提供关于亮氨酸代谢命运的信息,无论是作为氨基酸混合物中的游离氨基酸,还是作为蛋白质结合形式的固有标记酪蛋白。这将在大量和半限制亮氨酸摄入的条件下进行。此外,通过口服(2H2)-苯丙氨酸和静脉注射(2H5)-苯丙氨酸,我们可以比较在蛋白质或氨基酸供应充足和半受限的情况下,与示踪剂一起饲喂氨基酸或蛋白质的效果。通过两种示踪剂给药方式的比较,可以定量了解不同膳食条件下内脏提取亮氨酸和苯丙氨酸的情况。
英文摘要
This study will provide information concerning the metabolic fate of leucine ingested either as free amino acid in an amino acid mixture or in a protein bound form as intrinsiclly labeled casein. This will be done under conditions of a generous and a semi-limiting leucine intake. Additionally, by administering (2H2)-phenylalanine orally and (2H5)-phenylalanine intravenously this will enable us to compare the effects of feeding amino acids or protein together with the tracer under generous and semi-limiting protein or amino acid supply. Also, the comparison among the two routes of tracer administration will give us quantitative information about the splanchnic extraction of leucine and phenylalanine during different dietary conditions.
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THE EFFECT OF CREATINE SUPPLEMENTATION ON METHIONINE RE
  • 批准号:
    6982625
  • 项目类别:
  • 资助金额:
    $5.97万
  • 财政年份:
    2003
  • 负责人:
    VERNON R YOUNG
  • 依托单位:
CORE--MASS SPECTROMETRY LABORATORY
  • 批准号:
    6630907
  • 项目类别:
  • 资助金额:
    $10.37万
  • 财政年份:
    2002
  • 负责人:
    VERNON R YOUNG
  • 依托单位:
CORE--MASS SPECTROMETRY LABORATORY
  • 批准号:
    6500420
  • 项目类别:
  • 资助金额:
    $10.37万
  • 财政年份:
    2001
  • 负责人:
    VERNON R YOUNG
  • 依托单位:
CYSTEINE & GLUTATHIONE METABOLISM IN HEALTHY SUBJECTS
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