CYCLE SYNCHRONIZATION IN RHESUS MONKEYS

我们提供了一种服务，用于周期同步的方法， 其他研究者要求的黄体期延长。 这些 研究人员要求一群雌性恒河猴在 正常月经周期的黄体中期，都在同一天，所以 同样的病毒接种物可以用于阴道接种。 这种同步如下所示。 每日一次，用于指示月经。 当它发生时，每只猴子 从第16天开始注射孕酮。 当所有 研究猴子接受了至少8天的孕酮， 注射停止。 月经发生在最后2-3天 黄体酮注射液 在这个周期的第16天， 第二组黄体酮注射 接种已经完成 在最后一次注射黄体酮的一天里 这 程序提供了10只或更多猴子的研究组，所有 同步+ 1天在他们的周期阶段，并保持在黄体期 最多可容纳21人

We provide, as a service, a method for cycle synchronization and prolonged luteal phase as required by other investigators. These investigators require that a group of female rhesus monkeys be in the mid-luteal phase of a normal menstrual cycle, all on the same day, so that the same virus inoculums could be used for vaginal inoculation. This synchronization is provided as follows The monkeys are observed daily for indications of menses. When it occurs, each monkey is then injected with progesterone starting on day 16 of that cycle. When all study monkeys have received at least 8 days of progesterone the injections are stopped. Menses occurs 2-3 days of the last progesterone injection. On day 16 of that cycle the monkeys began a second series of progesterone injections. The inoculations are done on a single day during this last series of progesterone. This procedure has provided study groups of 10 or more monkeys, all synchronized + 1 day in their cycle stage and maintained in a luteal stage for up to 21