ARTIFICIAL BREEDING OF CHIMPANZEES

在过去一年中，继续努力改进人工繁殖 黑猩猩的方法。 超数排卵的方法已经 是用人类更年期促性腺激素研制的 的成功率 A.I.单次授精的成功率已经提高到80%以上， 受精周期的特定参数已经满足。 在这个 当这种识别是通过观察自发循环时， 然而，未来工作将致力于医源性引发这种 非常肥沃的循环。 生育能力的改变很可能 与子宫内膜发育和着床改变有关 率 由于限制繁殖的结果， 黑猩猩，我们正在加大努力， 使用体外受精和ICSI产生的胚胎的冷冻库。 迄今为止，胚胎已经从普通黑猩猩（P。 （C）和（D）的关系。 Atys）。 此外，我们在 研究鱼类和冷冻蛋白的潜在影响， 用于精液储存的冷冻保护剂。

Work has continued in the past year to improve artificial breeding methods for the chimpanzee. Methods for superovulation have been developed using human menopausal gonadotropins. The success rate of A.I. has been raised to over 80% for a single insemination when specific parameters of the inseminated cycle have been met. At this time such identification is by observation of the spontaneous cycle, however, future work will be directed to iatrogenic initiation of such highly fertile cycles. The alteration in fertility is likely associated with endometrial development and alteration of implantation rate. As a consequence of a restriction in breeding of the common chimpanzee, we are increasing efforts directed to creation and cryobanking of embryos created using In vitro fertilization and ICSI. To date embryos have been banked from the common chimpanzee (P. Troglodytes) and the sooty mangabey (c. Atys). In addition, we are studying the potential effects of fish an tifreeze proteins as cryoprotectants for semen storage.