MICRO BLOOD VESSEL VASOCONSTRICTION DURING BRAIN INJURY

我们正在研究大小动脉血管收缩的本质。 来自全脑缺血大鼠的脑组织(实验临床 死亡)。Hvem用于可视化免疫金定位。 特定表面膜相关整合素和免疫球蛋白 三维的感受器。Hvem的使用是至关重要的。 对于评估受体定位很重要，可能不是 结合使用扫描电子显微镜和/或薄层电子显微镜技术得出结论。Dr。 洛辛斯基今年曾多次访问资源中心。立体图像 记录在免疫金标记脑肿瘤囊泡上 并创建了一个测试立体重建。Lossinsky，A.S.，K.F. BATTLE，R.Pluta，M.J.Mossakowski和H.M.Wisniewski。(1997年) 细胞间黏附分子-1(ICAM-1/CD54)上调 发育和肿瘤中的囊泡-管状结构 血脑屏障。J.组织化学。细胞化学。(记者发稿)。

We are studying the nature of vasoconstriction in large arterioles from rat brains subjected to global ischemia (experimental clinical death). The HVEM is used to visualize the immunogold localization of specific surface membrane-associated integrin and immunoglobulin receptors in three dimensions. The use of the HVEM is critically important for evaluating receptor localization which may not be conclusive using combined SEM and/or thin section TEM techniques. Dr. Lossinsky visited the Resource several times this year. Stereo images were recorded on the HVEM of immunogold labeled brain tumor vesicles and a test Sterecon reconstruction was created. Lossinsky, A.S., K.F. Buttle, R. Pluta, M. J. Mossakowski and H.M. Wisniewski. (1997) Intercellular adhesion molecule-1 (ICAM-1/CD54) up-regulation in vesiculo-tubular structures (VTS) in the developmental and neoplastic blood-brain barrier. J. Histochem. Cytochem. (in press).