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EFFECT OF MEALS ON SERUM DHEA

EFFECT OF MEALS ON SERUM DHEA
膳食对血清 DHEA 的影响
批准号:
6298274
负责人:
FRANK SVEC
金额:
$1.97万
依托单位国家:
美国
项目类别:
财政年份:
1997
资助国家:
美国
项目状态:
已结题
起止时间:
1997-12-01 至 1999-06-30

项目摘要

项目成果

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中文摘要
翻译
脱氢表雄酮是一种肾上腺分泌的激素, 心脏病发作的人目前,人们对这些 控制血液中这种激素水平的因素。一 刺激肾上腺的条件是进食。 因此,可以预期,当一个人吃东西时,他的血液中的DHEA水平 应该上升。然而,主要研究者在初步调查中发现, 研究表明,实际上随着食物的摄入而下降。其他人已经表明 胰岛素增强DHEA从血清中的清除(或去除)。 通常认为,血清DHEA的降低是由 一顿饭的胰岛素增加。这个项目的目标是测试这个 假设 通过监测DHEA的下降,并将其与 增加胰岛素对标准餐的反应。
英文摘要
DHEA is a hormone made in the adrenal gland that appears to protect people from heart attacks. At this time little is known about those factors that control the level of this hormone in the blood. One condition that stimulates the adrenal gland is the consumption of a meal. Hence, it was anticipated that when a person ate, his blood level of DHEA should rise. However, the Principal Investigator found in preliminary studies, that the level actually goes down with meals. Others have shown that insulin enhances the clearance (or removal) of DHEA from the serum. It is often reasoned that the decrease in serum DHEA is caused by the rise in insulin of a meal. The goal of this project is to test this hypothesis by monitoring the fall of DHEA and comparing it with the increase in insulin in response to a standard meal.
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LEPTIN, BODY COMPOSITION, ADRENAL AND GONADAL HORMONES
  • 批准号:
    6970781
  • 项目类别:
  • 资助金额:
    $4.6万
  • 财政年份:
    2004
  • 负责人:
    FRANK SVEC
  • 依托单位:
DEHYDROEPIANDROSTERONE-SULFATE AS A BIOMARKER OF SENESCENCE IN MALE NHPS
  • 批准号:
    6970780
  • 项目类别:
  • 资助金额:
    $4.6万
  • 财政年份:
    2004
  • 负责人:
    FRANK SVEC
  • 依托单位:
LEPTIN, BODY COMPOSITION, ADRENAL AND GONADAL HORMONES
  • 批准号:
    6939808
  • 项目类别:
  • 资助金额:
    $5.32万
  • 财政年份:
    2003
  • 负责人:
    FRANK SVEC
  • 依托单位:
DEHYDROEPIANDROSTERONE-SULFATE AS A BIOMARKER OF SENESCENCE IN MALE NHPS
  • 批准号:
    6939707
  • 项目类别:
  • 资助金额:
    $5.32万
  • 财政年份:
    2003
  • 负责人:
    FRANK SVEC
  • 依托单位:
海外基金