LEUCINE & LYSINE: EFFECT OF TRACER PARTITIONING & DIETARY INDISPENSABLE NITROGEN

研究A：我们假设亮氨酸和赖氨酸示踪剂在禁食状态和进食状态之间的不同划分将产生不会妥协的数据，重要的是，我们之前的理解和实验发现，即粮农组织/世界卫生组织/联合国大学（1985）定义的亮氨酸和赖氨酸需求过低。因此，我们期望mit计算的日粮IAA最低需取量能得到进一步的支持。研究B：我们假设，在总氮摄入量为160 mg N/kg/d的恒定条件下，饮食中IAAs的下降（从“大量”[先前研究的]降至“中等”水平）不会显著影响亮氨酸和赖氨酸的平衡和需求，这将与我们之前研究中描述的相似（MIT亮氨酸需求为40 mg/kg/d，赖氨酸需求为30 mg/kg/d）。

Study A: We hypothesize that a different partitioning of leucine and lysine tracers, between fast and fed states, would generate data that would not compromise, significantly, our previous understanding and experimental findings that leucine and lysine requirements as defined by FAO/WHO/UNU (1985) are too low. Hence, we expect further support to the MIT-generated values of dietary IAA minimum requirements. Study B: We hypothesize that a decline in dietary IAAs (from "generous" [studied previously] to "intermediate" levels, at a constant total N intake of 160 mg N/kg/d, would not affect significantly leucine and lysine balances and requirements which would be expected to be similar to those described in our previous studies (MIT leucine requirement at 40 mg/kg/d, and lyine at 30 mg/kg/d).